Impact of the −174 G > C IL-6 Polymorphism on Bioelectrical Parameters in Obese Subjects after Laparoscopic Adjustable Gastric Banding
المؤلفون المشاركون
Migliore, Maria Rita
Di Renzo, Laura
Carbonelli, Maria Grazia
Rillo, Guido
Di Daniele, Nicola
Iacopino, Leonardo
Bianchi, Alessia
De Lorenzo, Antonino
Domino, Emidio
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-05-15
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Recent data demonstrated that the −174 G>C IL-6 polymorphism may account for differences in the therapeutic response to laparoscopic adjustable gastric banding (LAGB) surgery.
Objective.
We investigated the impact of −174 G>C IL-6 polymorphism on weight loss, body composition, and fluid distribution changes in obese subjects after LAGB.
Design and Outcome Measures.
Twenty obese subjects were selected and studied at baseline and 3 months after LAGB.
Genetic assessment of −174 G>C IL-6 polymorphism and anthropometric and bioelectrical impedance analysis were performed.
Results.
At baseline, C(+) carriers had a lower extracellular water (ECW) and higher intra-CW, phase angle (PA), reactance Xc, and Xc/height.
LAGB surgery determined significant reductions in weight and BMI.
After LAGB, in C(−) carriers, significant decreases in weight, BMI, and ECW and increases in BCM, BCMI, ICW, PA, and Xc/H were highlighted.
In C(+) carriers, significant reductions in weight, BMI, ICW, and PA and increases in ECW, Na/K, resistance (R), and R/height were obtained.
Significant higher reductions in BMI and Xc/H were observed in C(+) with respect to C(−) carriers.
Conclusions.
Genotyping of genetic variants, for example, the −174 G>C polymorphism of IL-6, gives the opportunity to predict therapeutic response, in terms of body composition outcomes after LAGB.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Di Renzo, Laura& Carbonelli, Maria Grazia& Bianchi, Alessia& Domino, Emidio& Migliore, Maria Rita& Rillo, Guido…[et al.]. 2012. Impact of the −174 G > C IL-6 Polymorphism on Bioelectrical Parameters in Obese Subjects after Laparoscopic Adjustable Gastric Banding. Journal of Obesity،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-454696
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Di Renzo, Laura…[et al.]. Impact of the −174 G > C IL-6 Polymorphism on Bioelectrical Parameters in Obese Subjects after Laparoscopic Adjustable Gastric Banding. Journal of Obesity No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-454696
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Di Renzo, Laura& Carbonelli, Maria Grazia& Bianchi, Alessia& Domino, Emidio& Migliore, Maria Rita& Rillo, Guido…[et al.]. Impact of the −174 G > C IL-6 Polymorphism on Bioelectrical Parameters in Obese Subjects after Laparoscopic Adjustable Gastric Banding. Journal of Obesity. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-454696
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-454696
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر