Genetic Characterization of Methicillin Resistant and Sensitive, Vancomycin Intermediate Staphylococcus aureus Strains Isolated from Different Iranian Hospitals
المؤلفون المشاركون
Ghazvini, Kiarash
Masoumi, Zahra
Naderi, Mahmood
Akbari, Mojtaba
Fazeli, Hosein
Samiee, Siamak Mirab
Azimian, Amir
Havaei, Seyed Asghar
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-20
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Global concerns have been raised due to upward trend of Vancomycin Intermediate Staphylococcus aureus (VISA) and Vancomycin Resistant Staphylococcus aureus (VRSA) reports which mean casting doubt on the absolute effectiveness of the last line of antibiotic treatment for S.
aureus, vancomycin.
Hence, epidemiological evaluation can improve global health care policies.
Methodology.
171 Isolates of Staphylococcus aureus were collected from different types of clinical samples in selected hospitals in Isfahan, Mashhad, and Tehran, Iran.
Then, they were evaluated by agar screening, disk diffusion, and MIC method to determine their resistance to vancomycin and methicillin.
The isolated VISA strains were then confirmed with genetic analysis by the evaluation of mecA and vanA genes, SCCmec, agr, and spa type, and also toxin profiles.
MLST was also performed.
Results and Conclusion.
Our data indicated that 67% of isolated S.
aureus strains were resistant to methicillin.
Furthermore, five isolates (2.9%) had intermediate resistance to vancomycin (VISA).
In contrast to usual association of VISA with MRSA strains, we found two isolates of MSSA-VISA.
Therefore, our data suggests a probable parallel growing trend of VISA towards MSSA, along with MRSA strains.
However, more samples are required to confirm these primarily data.
Moreover, genetic analysis of the isolated VISA strains revealed that these strains are endemic Asian clones.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Havaei, Seyed Asghar& Azimian, Amir& Fazeli, Hosein& Naderi, Mahmood& Ghazvini, Kiarash& Samiee, Siamak Mirab…[et al.]. 2012. Genetic Characterization of Methicillin Resistant and Sensitive, Vancomycin Intermediate Staphylococcus aureus Strains Isolated from Different Iranian Hospitals. ISRN Microbiology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-455198
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Havaei, Seyed Asghar…[et al.]. Genetic Characterization of Methicillin Resistant and Sensitive, Vancomycin Intermediate Staphylococcus aureus Strains Isolated from Different Iranian Hospitals. ISRN Microbiology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-455198
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Havaei, Seyed Asghar& Azimian, Amir& Fazeli, Hosein& Naderi, Mahmood& Ghazvini, Kiarash& Samiee, Siamak Mirab…[et al.]. Genetic Characterization of Methicillin Resistant and Sensitive, Vancomycin Intermediate Staphylococcus aureus Strains Isolated from Different Iranian Hospitals. ISRN Microbiology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-455198
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-455198
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر