Angiogenic Factors and Renal Disease in Pregnancy
المؤلفون المشاركون
Rana, Sarosh
Rhee, Julie S.
Young, Brett C.
المصدر
Case Reports in Obstetrics and Gynecology
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-07-28
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Background.
Preeclampsia is difficult to diagnose in patients with underlying renal disease and proteinuria.
Prior studies show that there is an angiogenic factor imbalance with elevated levels of antiangiogenic proteins soluble fms-like tyrosine kinase 1 (sFlt1) and soluble endoglin (sEng) and reduced levels of the proangiogenic protein, placental growth factor (PlGF) in women with preeclampsia.
These angiogenic biomarkers may be useful in distinguishing preeclampsia from other conditions of pregnancy, which may present with overlapping clinical characteristics.
Cases.
Case 1: A multiparous woman at 18 weeks gestation with nephrotic syndrome presented with hypertensive emergency and worsening renal insufficiency.
She underwent induction of labor for severe preeclampsia.
Her sFlt1 and sEng levels were at the 97 percentile while her PlGF level was undetectable (less than the 1st percentile).
Case 2: A nulliparous woman with lupus nephritis at 22 weeks gestation presented with fetal demise and heart failure.
Three weeks previously, the patient had developed thrombocytopenia and hypertensive urgency.
She underwent dilation and evacuation.
Her angiogenic profile was consistent with severe preeclampsia.
Conclusion.
Angiogenic factors may provide evidence to support a diagnosis of preeclampsia in patients with preexisting renal disease and proteinuria, conditions in which the classical definition of hypertension and proteinuria cannot be used.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rhee, Julie S.& Young, Brett C.& Rana, Sarosh. 2011. Angiogenic Factors and Renal Disease in Pregnancy. Case Reports in Obstetrics and Gynecology،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-459996
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rhee, Julie S.…[et al.]. Angiogenic Factors and Renal Disease in Pregnancy. Case Reports in Obstetrics and Gynecology No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-459996
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rhee, Julie S.& Young, Brett C.& Rana, Sarosh. Angiogenic Factors and Renal Disease in Pregnancy. Case Reports in Obstetrics and Gynecology. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-459996
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-459996
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر