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Comparison of Human-Like H1 (δ-Cluster) Influenza A Viruses in the Swine Host
المؤلفون المشاركون
Vincent, Amy L.
Janke, Bruce H.
Zanella, Eraldo L.
Lorusso, Alessio
Brockmeier, Susan L.
Loving, Crystal L.
Gramer, Marie R.
Gauger, Phillip C.
Ciacci Zanella, Janice R.
المصدر
Influenza Research and Treatment
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-06-03
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Influenza A viruses cause acute respiratory disease in swine.
Viruses with H1 hemagglutinin genes from the human seasonal lineage (δ-cluster) have been isolated from North American swine since 2003.
The objective of this work was to study the pathogenesis and transmission of δ-cluster H1 influenza viruses in swine, comparing three isolates from different phylogenetic subclusters, geographic locations, and years of isolation.
Two isolates from the δ2 subcluster, A/sw/MN/07002083/07 H1N1 (MN07) and A/sw/IL/00685/05 H1N1 (IL05), and A/sw/TX/01976/08 H1N2 (TX08) from the δ1 sub-cluster were evaluated.
All isolates caused disease and were transmitted to contact pigs.
Respiratory disease was apparent in pigs infected with MN07 and IL05 viruses; however, clinical signs and lung lesions were reduced in severity as compared to TX08.
On day 5 following infection MN07-infected pigs had lower virus titers than the TX08 pigs, suggesting that although this H1N1 was successfully transmitted, it may not replicate as efficiently in the upper or lower respiratory tract.
MN07 and IL05 H1N1 induced higher serum antibody titers than TX08.
Greater serological cross-reactivity was observed for viruses from the same HA phylogenetic sub-cluster; however, antigenic differences between the sub-clusters may have implications for disease control strategies for pigs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ciacci Zanella, Janice R.& Vincent, Amy L.& Zanella, Eraldo L.& Lorusso, Alessio& Loving, Crystal L.& Brockmeier, Susan L.…[et al.]. 2012. Comparison of Human-Like H1 (δ-Cluster) Influenza A Viruses in the Swine Host. Influenza Research and Treatment،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-463973
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ciacci Zanella, Janice R.…[et al.]. Comparison of Human-Like H1 (δ-Cluster) Influenza A Viruses in the Swine Host. Influenza Research and Treatment No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-463973
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ciacci Zanella, Janice R.& Vincent, Amy L.& Zanella, Eraldo L.& Lorusso, Alessio& Loving, Crystal L.& Brockmeier, Susan L.…[et al.]. Comparison of Human-Like H1 (δ-Cluster) Influenza A Viruses in the Swine Host. Influenza Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-463973
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-463973
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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