Therapeutic Effects of a New “Indigenous Vaccine” Developed Using Novel Native “Indian Bison Type” Genotype of Mycobacterium avium Subspecies paratuberculosis for the Control of Clinical Johne's Disease in Naturally Infected Goatherds in India
المؤلفون المشاركون
Singh, S. V.
Sharma, M. C.
Singh, P. K.
Singh, A. V.
Sohal, J. S.
المصدر
Veterinary Medicine International
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-02-14
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Therapeutic efficacy of an “Indigenous vaccine” has been evaluated with respect to a commercial vaccine (Gudair, Spain), for the control of clinical Johne's disease (JD) in naturally infected goatherds.
Seventy-one goats (JD positive) were randomly divided into 3 groups (“Bison”, “Gudair” and “Sham-immunized”).
After vaccination, goats were monitored for physical condition, morbidity, mortality, body weights, shedding of M.
paratuberculosis (MAP) in feces, internal condition and lesions, as well as humoral and cell-mediated immune responses for 210 days.
Study showed marked overall improvement in physical condition of vaccinated goats and average body weight gain was significantly higher (P<.05) in “Bison” group as compared to “Sham-immunized” goats.
Mortality due to JD was significantly (P<.05) lower in vaccinated groups than in “sham-immunized”.
Morbidity rates (due to diarrhea and weakness) were lower in “Bison” group as compared to other groups.
Died goats from vaccinated groups showed regression of gross JD lesions and regeneration of fat layer around visceral organs while “Sham-immunized” goats exhibited frank lesions.
Vaccinated goats had higher protective CMI response and also higher antibody titer for the trial period as compared to “Sham immunized”.
Both vaccines also reduced shedding of MAP in feces significantly (P<.05).
Though the two vaccines effectively restricted the severity of clinical symptoms of JD, however “Indigenous vaccine” was superior in many respects.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Singh, S. V.& Singh, P. K.& Singh, A. V.& Sohal, J. S.& Sharma, M. C.. 2010. Therapeutic Effects of a New “Indigenous Vaccine” Developed Using Novel Native “Indian Bison Type” Genotype of Mycobacterium avium Subspecies paratuberculosis for the Control of Clinical Johne's Disease in Naturally Infected Goatherds in India. Veterinary Medicine International،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-465065
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Singh, S. V.…[et al.]. Therapeutic Effects of a New “Indigenous Vaccine” Developed Using Novel Native “Indian Bison Type” Genotype of Mycobacterium avium Subspecies paratuberculosis for the Control of Clinical Johne's Disease in Naturally Infected Goatherds in India. Veterinary Medicine International No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-465065
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Singh, S. V.& Singh, P. K.& Singh, A. V.& Sohal, J. S.& Sharma, M. C.. Therapeutic Effects of a New “Indigenous Vaccine” Developed Using Novel Native “Indian Bison Type” Genotype of Mycobacterium avium Subspecies paratuberculosis for the Control of Clinical Johne's Disease in Naturally Infected Goatherds in India. Veterinary Medicine International. 2010. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-465065
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-465065
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر