Composite Indices Using 3 or 4 Components of the Core Data Set Have Similar Predictive Ability to Measure Disease Activity in RA : Evidence from the DANCER and REFLEX Studies
المؤلفون المشاركون
Reiss, William
Chung, Carol
Bergman, Martin J.
Turpcu, Adam
Wong, Pamela
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-04
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Understanding how disease-assessment indices perform in rheumatoid arthritis (RA) clinical trials can inform their use in routine practice.
The study objective was to assess the capacity of combinations of RA Core Data Set measures to distinguish rituximab from control treatment.
Methods.
Post hoc analysis of two randomised clinical trials was used.
Composite Efficacy Indices were derived by combining three or four RA Core Data Set measures from three possible sources: physician, patient, and laboratory.
Results.
All 105 Composite Efficacy Indices evaluated significantly distinguished rituximab from control treatment (P<10−7).
Generally, indices containing measures from three different sources had a greater capacity to distinguish rituximab from control treatment than indices containing three measures from one source.
Composite Efficacy Indices performed as well as validated indices such as DAS28, RAPID3, and CDAI.
Conclusions.
All indices composed of three or four RA Core Data Set measures have a similar capacity to detect treatment differences.
These results suggest that the precise measurement used is less important than whether any measurement is performed, although selection should be consistent for each patient.
Therefore, the choice of assessment tool should not be limited to a prescribed list and should instead be left to the clinician’s discretion.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bergman, Martin J.& Reiss, William& Chung, Carol& Wong, Pamela& Turpcu, Adam. 2013. Composite Indices Using 3 or 4 Components of the Core Data Set Have Similar Predictive Ability to Measure Disease Activity in RA : Evidence from the DANCER and REFLEX Studies. Autoimmune Diseases،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-466331
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bergman, Martin J.…[et al.]. Composite Indices Using 3 or 4 Components of the Core Data Set Have Similar Predictive Ability to Measure Disease Activity in RA : Evidence from the DANCER and REFLEX Studies. Autoimmune Diseases No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-466331
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bergman, Martin J.& Reiss, William& Chung, Carol& Wong, Pamela& Turpcu, Adam. Composite Indices Using 3 or 4 Components of the Core Data Set Have Similar Predictive Ability to Measure Disease Activity in RA : Evidence from the DANCER and REFLEX Studies. Autoimmune Diseases. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-466331
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-466331
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر