Early Onset Multiple Sclerosis Has Worse Prognosis Than Adult Onset Multiple Sclerosis Based on Cognition and Magnetic Resonance Imaging
المؤلفون المشاركون
Özakbaş, Serkan
Kaya, Derya
Idiman, Egemen
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-07
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Objectives.
In the present study, we aimed to compare the childhood and adult onset multiple sclerosis patients prospectively in their adulthood on the basis of clinical and magnetic resonance imaging (MRI) findings and cognitive impairment, which have not been performed before.
Patients and Methods.
Forty-six patients in whom the disease onset occurred before 16 years of age were included in the present study.
Study subjects were compared with 64 randomly included adult onset patients.
Results.
Mean disease duration, clinical course, and female to male ratio did not differ in the groups.
Cerebellar/brainstem and spinal involvement at onset were significantly higher in EOMS than in AOMS.
Difference in MSFC between baseline and at the end of the 5th year was significantly worse in EOMS population (P=0.02).
The most significant difference was found in Paced Auditory Serial Addition Test (PASAT) (P=0.008).
Differences between baseline and at the end of the 5th year on the basis of T1 hypointense lesions were significantly higher in early onset MS than in adult onset MS patients (P=0.02).
Conclusions.
Early onset MS seems to have worse prognosis than that of adult onset MS on the basis of clinical manifestation, cognitive impairment, and MRI parameters.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Özakbaş, Serkan& Kaya, Derya& Idiman, Egemen. 2012. Early Onset Multiple Sclerosis Has Worse Prognosis Than Adult Onset Multiple Sclerosis Based on Cognition and Magnetic Resonance Imaging. Autoimmune Diseases،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-481094
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Özakbaş, Serkan…[et al.]. Early Onset Multiple Sclerosis Has Worse Prognosis Than Adult Onset Multiple Sclerosis Based on Cognition and Magnetic Resonance Imaging. Autoimmune Diseases No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-481094
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Özakbaş, Serkan& Kaya, Derya& Idiman, Egemen. Early Onset Multiple Sclerosis Has Worse Prognosis Than Adult Onset Multiple Sclerosis Based on Cognition and Magnetic Resonance Imaging. Autoimmune Diseases. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-481094
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-481094
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر