Yttrium-90 Radioembolization for Colorectal Cancer Liver Metastases : A Single Institution Experience
المؤلفون المشاركون
Gamblin, T. Clark
Joyce, Judith
Nastasi, Bryon E.
Zajko, Albert
Amesur, Nikhil
Nace, Gary W.
Sheetz, Michael
Steel, Jennifer L.
المصدر
International Journal of Surgical Oncology
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-03-20
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Purpose.
We sought to evaluate our experience using yttrium-90 (90Y) resin microsphere hepatic radioembolization as salvage therapy for liver-dominant metastatic colorectal cancer (mCRC).
Methods.
A retrospective review of consecutive patients with unresectable mCRC who were treated with 90Y after failing first and second line systemic chemotherapy.
Demographics, treatment dose, biochemical and radiographic response, toxicities, and survival were examined.
Results.
Fifty-one patients underwent 90Y treatments of which 69% were male.
All patients had previously undergone extensive chemotherapy, 31% had undergone previous liver-directed therapy and 24% had a prior liver resection.
Using RECIST criteria, either stable disease or a partial response was seen in 77% of patients.
Overall median survival from the time of first 90Y treatment was 10.2 months (95% CI = 7.5–13.0).
The absence of extrahepatic disease at the time of treatment with 90Y was associated with an improved survival, median survival of 17.0 months (95% CI = 6.4–27.6), compared to those with extrahepatic disease at the time of treatment with 90Y, 6.7 months (95% CI = 2.7–10.6 Conclusion: 90Y therapy is a safe locoregional therapy that provides an important therapeutic option to patients who have failed first and second line chemotherapy and have adequate liver function and performance status.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nace, Gary W.& Steel, Jennifer L.& Amesur, Nikhil& Zajko, Albert& Nastasi, Bryon E.& Joyce, Judith…[et al.]. 2011. Yttrium-90 Radioembolization for Colorectal Cancer Liver Metastases : A Single Institution Experience. International Journal of Surgical Oncology،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-481640
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nace, Gary W.…[et al.]. Yttrium-90 Radioembolization for Colorectal Cancer Liver Metastases : A Single Institution Experience. International Journal of Surgical Oncology No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-481640
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nace, Gary W.& Steel, Jennifer L.& Amesur, Nikhil& Zajko, Albert& Nastasi, Bryon E.& Joyce, Judith…[et al.]. Yttrium-90 Radioembolization for Colorectal Cancer Liver Metastases : A Single Institution Experience. International Journal of Surgical Oncology. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-481640
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-481640
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر