Kinship and Leprosy in the Contacts of Leprosy Patients : Cohort at the Souza Araújo Outpatient Clinic, Rio de Janeiro, RJ, 1987–2010
المؤلفون المشاركون
Duppre, Nadia Cristina
Hacker, Mariana Andréa
Sarno, Euzenir Nunes
dos Santos, Daiane Santos
Nery, José Augusto da Costa
Sales, Anna Maria
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-04-10
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
A broad variety of factors have been associated with leprosy among contacts, including socioeconomic, epidemiological, and genetic characteristics.
Data from 7,174 contacts of leprosy patients from a leprosy outpatient clinic in Rio de Janeiro, Brazil, 1987–2010, were analyzed to investigate the effects of kinship, individual, and contextual factors on leprosy.
Multivariate analyses were performed using a robust estimation method.
In the prevalence analysis, close kinship (sibling OR = 2.75, offspring OR = 2.00, and other relatives OR = 1.70), socioeconomic factors, and the duration of exposure to the bacillus were associated to leprosy.
In the incidence analysis, significant risks were found for all categories of kinship (parents RR = 10.93, spouse, boyfriend/girlfriend, and bride/groom RR = 7.53, sibling RR = 7.03, offspring RR = 5.34, and other relatives RR = 3.71).
Once the treatment of the index case was initiated, other factors lost their significance, and the index case bacteriological index and BCG (Bacillus Calmette-Guérin vaccine) protection had a greater impact.
Our findings suggested that both genetic susceptibility and physical exposure play an important role in the epidemiology of leprosy, but it was not possible establishing the role of genetic factor.
Analyses of other factors related to the genotype of individuals, such as genetic polymorphisms, are needed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
dos Santos, Daiane Santos& Duppre, Nadia Cristina& Sales, Anna Maria& Nery, José Augusto da Costa& Sarno, Euzenir Nunes& Hacker, Mariana Andréa. 2013. Kinship and Leprosy in the Contacts of Leprosy Patients : Cohort at the Souza Araújo Outpatient Clinic, Rio de Janeiro, RJ, 1987–2010. Journal of Tropical Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-483796
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
dos Santos, Daiane Santos…[et al.]. Kinship and Leprosy in the Contacts of Leprosy Patients : Cohort at the Souza Araújo Outpatient Clinic, Rio de Janeiro, RJ, 1987–2010. Journal of Tropical Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-483796
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
dos Santos, Daiane Santos& Duppre, Nadia Cristina& Sales, Anna Maria& Nery, José Augusto da Costa& Sarno, Euzenir Nunes& Hacker, Mariana Andréa. Kinship and Leprosy in the Contacts of Leprosy Patients : Cohort at the Souza Araújo Outpatient Clinic, Rio de Janeiro, RJ, 1987–2010. Journal of Tropical Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-483796
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-483796
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر