Redefining Lumpectomy Using a Modification of the “Sick Lobe” Hypothesis and Ductal Anatomy
المؤلفون المشاركون
Bong, J.
Dooley, William C.
Parker, J.
المصدر
International Journal of Breast Cancer
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-06-30
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Objectives.
The “Sick Lobe” hypothesis states that breast cancers evolve from entire lobes or portions of lobes of the breast where initiation events have occurred early in development.
The implication is that some cancers are isolated events and others are truly multi-focal but limited to single lobar-ductal units.
Methods.
This is a single surgeon retrospective review of early stage breast cancer lumpectomy patients treated from 1/2000 to 2/2005.
Ductal endoscopy was used direct lumpectomy surgical margins by defining ductal anatomy and mapping proliferative changes within the sick lobe for complete excision.
Results.
Breast conservation surgery for stage 0–2 breast cancer with an attempt to perform endoscopy in association with therapeutic lumpectomy was performed in 554 patients (successful endoscopy in 465 cases).
With an average followup of >5 years for the entire group, annual hazard rate for local failure in traditional lumpectomy without ductal mapping was 0.97%/yr.
and for lumpectomy with ductal mapping and excision of entire sick lobe was 0.18%/yr.
With endoscopy, 42% of patients were found to have extensive disease within their “sick lobe.” Conclusions.
Targeting breast cancer lumpectomy using endoscopy and excision of regional associated proliferation seems associated with lower recurrence in this non-randomized series.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dooley, William C.& Bong, J.& Parker, J.. 2011. Redefining Lumpectomy Using a Modification of the “Sick Lobe” Hypothesis and Ductal Anatomy. International Journal of Breast Cancer،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-493749
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dooley, William C.…[et al.]. Redefining Lumpectomy Using a Modification of the “Sick Lobe” Hypothesis and Ductal Anatomy. International Journal of Breast Cancer No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-493749
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dooley, William C.& Bong, J.& Parker, J.. Redefining Lumpectomy Using a Modification of the “Sick Lobe” Hypothesis and Ductal Anatomy. International Journal of Breast Cancer. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-493749
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-493749
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر