Differences in Epidural and Analgesic Use in Patients with Apparent Stage I Endometrial Cancer Treated by Open versus Laparoscopic Surgery : Results from the Randomised LACE Trial

المؤلفون المشاركون

Obermair, Andreas
Janda, Monika
Baker, Jannah
Belavy, David

المصدر

Minimally Invasive Surgery

العدد

المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2013-07-14

دولة النشر

مصر

عدد الصفحات

5

التخصصات الرئيسية

الطب البشري

الملخص EN

Objectives.

We compared postoperative analgesic requirements between women with early stage endometrial cancer treated by total abdominal hysterectomy (TAH) or total laparoscopic hysterectomy (TLH).

Methods.

760 patients with apparent stage I endometrial cancer were treated in the international, multicentre, prospective randomised trial (LACE) by TAH (n=353) or TLH (n=407) (2005–2010).

Epidural, opioid, and nonopioid analgesic requirements were collected until ten months after surgery.

Results.

Baseline demographics and analgesic use were comparable between treatment arms.

TAH patients were more likely to receive epidural analgesia than TLH patients (33% versus 0.5%, P<0.001) during the early postoperative phase.

Although opioid use was comparable in the TAH versus TLH groups during postoperative 0–2 days (99.7% versus 98.5%, P=0.09), a significantly higher proportion of TAH patients required opioids 3–5 days (70% versus 22%, P<0.0001), 6–14 days (35% versus 15%, P<0.0001), and 15–60 days (15% versus 9%, P=0.02) after surgery.

Mean pain scores were significantly higher in the TAH versus TLH group one (2.48 versus 1.62, P<0.0001) and four weeks (0.89 versus 0.63, P=0.01) following surgery.

Conclusion.

Treatment of early stage endometrial cancer with TLH is associated with less frequent use of epidural, lower post-operative opioid requirements, and better pain scores than TAH.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Baker, Jannah& Janda, Monika& Belavy, David& Obermair, Andreas. 2013. Differences in Epidural and Analgesic Use in Patients with Apparent Stage I Endometrial Cancer Treated by Open versus Laparoscopic Surgery : Results from the Randomised LACE Trial. Minimally Invasive Surgery،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-496976

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Baker, Jannah…[et al.]. Differences in Epidural and Analgesic Use in Patients with Apparent Stage I Endometrial Cancer Treated by Open versus Laparoscopic Surgery : Results from the Randomised LACE Trial. Minimally Invasive Surgery No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-496976

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Baker, Jannah& Janda, Monika& Belavy, David& Obermair, Andreas. Differences in Epidural and Analgesic Use in Patients with Apparent Stage I Endometrial Cancer Treated by Open versus Laparoscopic Surgery : Results from the Randomised LACE Trial. Minimally Invasive Surgery. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-496976

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-496976