Use and Misuse of a Biomarker : Contrast-Medium-Induced Nephropathy and Serum Creatinine
المؤلف
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-06-06
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Two different types of contrast media are being used: low-osmolar and isoosmolar contrast media (LOCM, IOCM).
Both types induce renal failure.
Serum creatinine is routinely used as a marker of renal impairment in many clinical settings.
A variety of studies and meta-analyses addressed the differential safety of contrast media with divergent osmolarity.
Unfortunately, research in this field is lacking standardized endpoints, as different levels of creatinine increase are used as a surrogate for renal failure, and additionally, serum creatinine levels are influenced by a variety of pathophysiological conditions and thus susceptible for marker artifacts.
This is one explanation why conflicting results have been published regarding the different safety of contrast media favoring either LOCM or IOCM.
Viscosity which is higher in IOCM rather than osmolarity determines the potential of a CM to induce renal failure.
High viscosity reduces flow in renal tubules and vessels and thus impairs renal filtration.
Thus, the most effective prevention measure for renal failure is reducing the concentration of contrast media and adequate hydration.
In emergency situations, hydration as well as kidney status is commonly unknown, and LOCM are indicated due to their lower viscosity and to their greater water-binding capacity to reduce the risk of renal failure.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Persson, Pontus B.. 2013. Use and Misuse of a Biomarker : Contrast-Medium-Induced Nephropathy and Serum Creatinine. Conference Papers in Medicine،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-499118
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Persson, Pontus B.. Use and Misuse of a Biomarker : Contrast-Medium-Induced Nephropathy and Serum Creatinine. Conference Papers in Medicine No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-499118
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Persson, Pontus B.. Use and Misuse of a Biomarker : Contrast-Medium-Induced Nephropathy and Serum Creatinine. Conference Papers in Medicine. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-499118
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-499118
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر