Proteomics of Uveal Melanoma : A Minireview

المؤلفون المشاركون

Vorum, Henrik
Abildgaard, Søren K. O.

المصدر

Journal of Oncology

العدد

المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-11، 11ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2013-09-03

دولة النشر

مصر

عدد الصفحات

11

التخصصات الرئيسية

الأمراض
الطب البشري

الملخص EN

Uveal melanoma (UM) continues to be associated with a high mortality rate of up to 50% due to metastatic spread primarily to the liver.

Currently there are relatively effective treatments for the primary tumor, though the management of the metastatic disease remains inadequate.

Conventional diagnostic tools have a low sensitivity for detecting metastasis, and early detection of metastatic spread would allow more treatment options that could ultimately increase survival of UM patients.

Advanced proteomic methods have already helped to find potential biomarkers associated with UM pathogenesis and metastasis.

In the present review we discuss the field of proteomics in relation to studies elucidating biomarkers of UM, where proteins such as S-100β, osteopontin (OPN), and melanoma inhibitory activity (MIA) have been shown to be associated with metastasis.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Abildgaard, Søren K. O.& Vorum, Henrik. 2013. Proteomics of Uveal Melanoma : A Minireview. Journal of Oncology،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-500804

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Abildgaard, Søren K. O.& Vorum, Henrik. Proteomics of Uveal Melanoma : A Minireview. Journal of Oncology No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-500804

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Abildgaard, Søren K. O.& Vorum, Henrik. Proteomics of Uveal Melanoma : A Minireview. Journal of Oncology. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-500804

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-500804