Predictive Factors of Response in HER2-Positive Breast Cancer Treated by Neoadjuvant Therapy

المؤلفون المشاركون

Guiu, S.
Coudert, B.
Toure, M.
Mouret Reynier, M. A.

المصدر

Journal of Oncology

العدد

المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2013-04-29

دولة النشر

مصر

عدد الصفحات

9

التخصصات الرئيسية

الأمراض
الطب البشري

الملخص EN

Since 2005, major progresses have been made in the neoadjuvant treatment of HER2-positive breast cancer.

Trastuzumab introduction associated with chemotherapy has been the first major step leading to the improvement of the complete pathological response rate and, like in the adjuvant studies, better survivals.

Dual HER2 blockade has been the next step and trastuzumab is associated now with other anti-HER2 therapies like lapatinib or pertuzumab, the latter being much more easy to use in combination with chemotherapy.

Additional knowledge is necessary to better define within the HER2 tumor subgroup which patients could benefit more from targeted therapies.

Different biomarkers have been studied to predict the response after anti-HER2 neoadjuvant therapies but until now none has been validated.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Guiu, S.& Mouret Reynier, M. A.& Toure, M.& Coudert, B.. 2013. Predictive Factors of Response in HER2-Positive Breast Cancer Treated by Neoadjuvant Therapy. Journal of Oncology،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-503583

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Guiu, S.…[et al.]. Predictive Factors of Response in HER2-Positive Breast Cancer Treated by Neoadjuvant Therapy. Journal of Oncology No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-503583

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Guiu, S.& Mouret Reynier, M. A.& Toure, M.& Coudert, B.. Predictive Factors of Response in HER2-Positive Breast Cancer Treated by Neoadjuvant Therapy. Journal of Oncology. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-503583

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-503583