Association of Lipids with Oxidative Stress Biomarkers in Subclinical Hypothyroidism
المؤلفون المشاركون
Loro, Vania Lucia
de Menezes, Charlene C.
Santi, Adriana
Medeiros Frescura Duarte, Marta Maria
المصدر
International Journal of Endocrinology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-29
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
The aim of the present study was to evaluate the oxidative stress biomarkers in patients with subclinical hypothyroidism (n=20) and health controls (n=20).
Subjects and Methods.
Total cholesterol (TC), triglycerides (TGs), low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), thiobarbituric acid reactive substances (TBARSs), catalase (CAT), superoxide dismutase (SOD), and arylesterase (ARE) were analyzed.
Results.
TC, LDL-C, TBARS, and CAT were higher in subclinical hypothyroidism patients, whereas SOD did not change.
Arylesterase activity was significantly lower in the SH group, compared with the control group.
Correlation analyses revealed the association of lipids (TC and LDL-C) with both oxidative stress biomarkers and thyrotropin (TSH).
Thyroid hormones were correlated only with triglyceride levels.
In addition, TSH was significantly correlated with TBARS, CAT, and SOD.
However, no significant correlations were observed after controlling TC levels.
Conclusions.
We found that SH patients are under increased oxidative stress manifested by reduced ARE activity and elevated lipoperoxidation and CAT activity.
Secondary hypercholesterolemia to thyroid dysfunction and not hypothyroidism per se appears to be associated with oxidative stress in subclinical hypothyroidism.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Santi, Adriana& Medeiros Frescura Duarte, Marta Maria& de Menezes, Charlene C.& Loro, Vania Lucia. 2012. Association of Lipids with Oxidative Stress Biomarkers in Subclinical Hypothyroidism. International Journal of Endocrinology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-503727
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Santi, Adriana…[et al.]. Association of Lipids with Oxidative Stress Biomarkers in Subclinical Hypothyroidism. International Journal of Endocrinology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-503727
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Santi, Adriana& Medeiros Frescura Duarte, Marta Maria& de Menezes, Charlene C.& Loro, Vania Lucia. Association of Lipids with Oxidative Stress Biomarkers in Subclinical Hypothyroidism. International Journal of Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-503727
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-503727
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر