Inflammatory Characteristics of Stenotic Aortic Valves : A Comparison between Rheumatic and Nonrheumatic Aortic Stenosis
المؤلفون المشاركون
Wallby, Lars
Steffensen, Thora
Jonasson, Lena
Broqvist, Mats
المصدر
Cardiology Research and Practice
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-02-14
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Although our comprehension of nonrheumatic aortic stenosis (NRAS) has increased substantially during the last decade, less is known about the histopathology of rheumatic aortic stenosis (RAS).
The aim of this study was to investigate rheumatic aortic stenosis by means of analyses previously used in nonrheumatic stenosis.
Material and Methods.
Valve specimens were obtained from 39 patients referred to hospital due to significant aortic stenosis.
According to established macroscopic criteria the valves were divided into two groups consisting of 29 NRAS and 10 RAS valves.
Mononuclear inflammatory cells and apolipoproteins were investigated using immunohistochemical analyses.
Results.
The localisation of calcification differed in tricuspid nonrheumatic valves when compared to bicuspid nonrheumatic and rheumatic valves.
The RAS valves revealed a lower degree of T lymphocyte infiltration compared with the NRAS valves.
Infiltration of macrophages was seen in all valves and there were no differences regarding deposition of apolipoprotein.
Conclusion.
Rheumatic and nonrheumatic aortic stenotic valves show a similar and significant chronic inflammation.
The similarities regarding the localisation of calcification indicate that the valve anomaly/morphology can influence the pathogenesis of aortic stenosis.
Finally, our findings highlight the question of a postinflammatory valvular disease of other causes than rheumatic fever.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wallby, Lars& Steffensen, Thora& Jonasson, Lena& Broqvist, Mats. 2013. Inflammatory Characteristics of Stenotic Aortic Valves : A Comparison between Rheumatic and Nonrheumatic Aortic Stenosis. Cardiology Research and Practice،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-506177
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wallby, Lars…[et al.]. Inflammatory Characteristics of Stenotic Aortic Valves : A Comparison between Rheumatic and Nonrheumatic Aortic Stenosis. Cardiology Research and Practice No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-506177
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wallby, Lars& Steffensen, Thora& Jonasson, Lena& Broqvist, Mats. Inflammatory Characteristics of Stenotic Aortic Valves : A Comparison between Rheumatic and Nonrheumatic Aortic Stenosis. Cardiology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-506177
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-506177
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر