Two-Hour Lactate Clearance Predicts Negative Outcome in Patients with Cardiorespiratory Insufficiency
المؤلفون المشاركون
Guiotto, Giovanna
Paladino, Fiorella
Antonaglia, Vittorio
Scott, Sean
Schiraldi, Fernando
المصدر
Critical Care Research and Practice
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-06-28
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
To evaluate 2-hour lactate clearance as a prognostic marker in acute cardiorespiratory insufficiency.
Design.
Prospective observational study.
Setting.
Emergency Department (ED) and 16-bed medical High Dependency Unit (HDU).
Methods and Main Results.
95 consecutive admissions from the ED for acute cardiorespiratory insufficiency were prospectively enrolled.
Arterial lactate concentration was assessed at ED arrival and 1, 2, 6, and 24 hours later.
The predictive value of 2-hour lactate clearance was evaluated for negative outcomes defined as hospital mortality or need for endotracheal intubation versus positive outcomes defined as discharge or transfer to a general medical ward.
Logistic regression and ROC curves found 2-hour lactate clearance >15% was a strong predictor of negative outcome (P<.0001) with a sensitivity of 86% (95%CI=67%–95%) and a specificity of 91% (95%CI=82%–96%), Positive predictive value was 80% (95%CI=61%–92%), and negative predictive value was 92% (95%CI=84%–98%).
Conclusions.
Systematic monitoring of lactate clearance at 2 hours can be used in to identify patients at high risk of negative outcome and perhaps to tailor more aggressive therapy.
Equally important is that a 2-hour lactate clearance >15% is highly predictive of positive outcome and may reassure clinicians that the therapeutic approach is appropriate.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Scott, Sean& Antonaglia, Vittorio& Guiotto, Giovanna& Paladino, Fiorella& Schiraldi, Fernando. 2010. Two-Hour Lactate Clearance Predicts Negative Outcome in Patients with Cardiorespiratory Insufficiency. Critical Care Research and Practice،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-507917
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Scott, Sean…[et al.]. Two-Hour Lactate Clearance Predicts Negative Outcome in Patients with Cardiorespiratory Insufficiency. Critical Care Research and Practice No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-507917
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Scott, Sean& Antonaglia, Vittorio& Guiotto, Giovanna& Paladino, Fiorella& Schiraldi, Fernando. Two-Hour Lactate Clearance Predicts Negative Outcome in Patients with Cardiorespiratory Insufficiency. Critical Care Research and Practice. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-507917
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-507917
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر