Acquired Haemophilia A in the Elderly : Case Reports
المؤلفون المشاركون
Coppola, Antonio
Tufano, Antonella
De Gregorio, Angela Maria
Cimino, Ernesto
Di Minno, Giovanni
Guida, Anna
Cerbone, Anna Maria
المصدر
Current Gerontology and Geriatrics Research
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-03-03
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Acquired hemophilia A (AHA) is a very rare disease, caused by the development of autoantibodies, directed against circulating factor VIII of coagulation.
Age distribution is bimodal, with a first peak occurring among young women in the postpartum period, and a second major peak of incidence among elderly patients in whom it is frequently associated with malignancy and drugs.
This disease often represents a life-threatening bleeding condition, especially in the elderly, thus requiring a prompt therapeutic intervention, including control of acute bleeding and eradication of the inhibitor by immunosuppressive therapy.
The diagnosis of AHA should be considered in any elderly patient who presents with bleeding and prolonged activated Partial Thromboplastin Time.
Moreover, the coexistence of a series of underlying diseases associated with AHA should be always searched for.
An early recognition and an adequate treatment of this coagulation disorder and of the possible associated diseases play a significant role for a favourable outcome, but concomitant morbidities in the elderly may limit aggressive therapy and may complicate the clinical scenario.
We report 3 consecutive elderly patients successfully treated with recombinant activated factor VII and standard immunosuppressive regimens, with remission of the disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tufano, Antonella& Coppola, Antonio& Guida, Anna& Cimino, Ernesto& De Gregorio, Angela Maria& Cerbone, Anna Maria…[et al.]. 2010. Acquired Haemophilia A in the Elderly : Case Reports. Current Gerontology and Geriatrics Research،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-508792
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tufano, Antonella…[et al.]. Acquired Haemophilia A in the Elderly : Case Reports. Current Gerontology and Geriatrics Research No. 2010 (2010), pp.1-5.
https://search.emarefa.net/detail/BIM-508792
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tufano, Antonella& Coppola, Antonio& Guida, Anna& Cimino, Ernesto& De Gregorio, Angela Maria& Cerbone, Anna Maria…[et al.]. Acquired Haemophilia A in the Elderly : Case Reports. Current Gerontology and Geriatrics Research. 2010. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-508792
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-508792
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر