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The Budding Yeast “Saccharomyces cerevisiae” as a Drug Discovery Tool to Identify Plant-Derived Natural Products with Anti-Proliferative Properties
المؤلفون المشاركون
Bellirou, Ahmed
Brown, Grant W.
Qaddouri, Bouchra
Bellaoui, Mohammed
Hamal, Abdellah
Melhaoui, Ahmed
Guaadaoui, Abdelkarim
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-06-23
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
The budding yeast Saccharomyces cerevisiae is a valuable system to study cell-cycle regulation, which is defective in cancer cells.
Due to the highly conserved nature of the cell-cycle machinery between yeast and humans, yeast studies are directly relevant to anticancer-drug discovery.
The budding yeast is also an excellent model system for identifying and studying antifungal compounds because of the functional conservation of fungal genes.
Moreover, yeast studies have also contributed greatly to our understanding of the biological targets and modes of action of bioactive compounds.
Understanding the mechanism of action of clinically relevant compounds is essential for the design of improved second-generation molecules.
Here we describe our methodology for screening a library of plant-derived natural products in yeast in order to identify and characterize new compounds with anti-proliferative properties.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Qaddouri, Bouchra& Guaadaoui, Abdelkarim& Bellirou, Ahmed& Hamal, Abdellah& Melhaoui, Ahmed& Brown, Grant W.…[et al.]. 2011. The Budding Yeast “Saccharomyces cerevisiae” as a Drug Discovery Tool to Identify Plant-Derived Natural Products with Anti-Proliferative Properties. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-511128
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Qaddouri, Bouchra…[et al.]. The Budding Yeast “Saccharomyces cerevisiae” as a Drug Discovery Tool to Identify Plant-Derived Natural Products with Anti-Proliferative Properties. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-511128
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Qaddouri, Bouchra& Guaadaoui, Abdelkarim& Bellirou, Ahmed& Hamal, Abdellah& Melhaoui, Ahmed& Brown, Grant W.…[et al.]. The Budding Yeast “Saccharomyces cerevisiae” as a Drug Discovery Tool to Identify Plant-Derived Natural Products with Anti-Proliferative Properties. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-511128
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-511128
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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