Nodular Lymphocyte Predominant Hodgkin Lymphoma versus T-CellHistiocyte-Rich Large B-Cell Lymphoma : A Diagnostic Challenge
المؤلفون المشاركون
Gottesman, Susan R. S.
Rets, Anton V.
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-07
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Lymphomas with overlapping histological features of two distinct entities cause difficulty in classification.
Their classification is of particular significance when the two alternatives require different treatment modalities.
We present a diagnostically challenging case of a nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) with features of T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL).
Our patient is a 39-year-old woman who presented with painless subclavicular and axillary lymphadenopathy.
The biopsied lymph node showed diffuse architectural effacement and scattered large neoplastic cells with large irregular nuclei and prominent nucleoli.
These cells were positive for CD20 and Bcl-6 and negative for CD15, CD30, IgD, and Bcl-2.
The background cells were predominantly T lymphocytes, whereas B cells were markedly depleted.
The lymph node was interpreted as NLPHL, consistent with THRLBCL-like variant.
NLPHL, especially THRLBC-like variant, and de novo THRLBCL are characterized by significant morphologic and immunophenotypic overlap.
Our case demonstrates a rare predominance of background T-cells in NLPHL and emphasizes the importance of thorough evaluation of multiple morphologic and immunophenotypic features as an essential approach for arriving at the correct diagnosis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rets, Anton V.& Gottesman, Susan R. S.. 2014. Nodular Lymphocyte Predominant Hodgkin Lymphoma versus T-CellHistiocyte-Rich Large B-Cell Lymphoma : A Diagnostic Challenge. Case Reports in Pathology،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-511223
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rets, Anton V.& Gottesman, Susan R. S.. Nodular Lymphocyte Predominant Hodgkin Lymphoma versus T-CellHistiocyte-Rich Large B-Cell Lymphoma : A Diagnostic Challenge. Case Reports in Pathology No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-511223
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rets, Anton V.& Gottesman, Susan R. S.. Nodular Lymphocyte Predominant Hodgkin Lymphoma versus T-CellHistiocyte-Rich Large B-Cell Lymphoma : A Diagnostic Challenge. Case Reports in Pathology. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-511223
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-511223
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر