Paget’s disease of the skull

الملخص EN

Paget’s disease is a chronic disorder of unknown etiology that mainly affects the elderly.

It is characterized by focal areas of excessive osteoclastic bone resorption with associated increase in osteoblastic bone formation.

Diagnosis is made commonly after performing radiological studies, especially bone scintigraphy.

We report a patient with high levels of serum alkaline phosphatase that was diagnosed of Paget’s disease of the skull and treated with Alendronate