انتشار الفيروس الصغير B19 في مصول مجموعة من أطفال مدينة دمشق في سورية

الملخص EN

Parvovirus B19 infects children and adults, causing erythema infectiosum, polyarthritis, aplastic crisis and chronic anemia in patients with hematological or immunological disorders, and fetal hydrops or fetal death.

This study aims to estimate the prevalence of B19 IgG and IgM antibodies in Damascus, Syria.

Specimens were obtained randomly from 280 children (139 males and 141 females), aged from one month to 17 years, from Children Hospital in Damascus, at the period between January 2013 and April 2013.

B19V specific IgG and IgM antibodies were detected in serum, by a commercial indirect enzyme-linked immunosorbent assay.

We found 83 of 280 children (29.64%) were seropositive for B19 IgG antibody, whereas 4 (1.43%) were seropositive for IgM.

The difference in the prevalence of B19 IgG antibodies between genders was not statistically significant (p=0.84), but the prevalence of antibodies increased significantly (p=0.012) in the age group of 10–17 years, compared with younger children.

As conclusion, this study revealed an influence of geographic differences on transmission of parvovirus B19, and detected the increase of B19 IgG antibodies with age.

The study also showed that there was no relation between seropositivity and sex