التأثيرات العلاجية لبعض أنواع العائلة النجيلية في تحسين المعالم غير السوية المرافقة للإصابة بالسكري في ذكور الجرذان

الملخص EN

The present study aimed to investigate the positive role of two plant belongs to the gramineae family (barley and oats ) to ameliorate some physiological and histological parameters in alloxane – induced diabetic rats.

Twenty sexually mature rats were divided into equal groups , the first served as negative control (C) , the second diabetic group treated with water tap(T1) , the third diabetic group & treated with ethanolic extract of barley (20 mg/Kg B.W.)(T2) , the fourth diabetic & treated with ethanolic extract of oats (20 mg/Kg B.W) (T3) .The results reveals a significant increase under (p≤0.05) in the levels of blood glucose , AST , ALT , APH , serum Cholesterol , abnormal sperm count and significant decrease in the RBC count , total protein , total sperm count compared with control group.

In the same time the results showed that a significant decease under (p≤0.05) in the levels of blood glucose , AST,ALT ,APH ,WBC count , serum Cholesterol ,ratio of abnormal sperm count and a significant increase in the RBC count , total protein , normal sperm count in the T2 & T3 compared with T3 whereas no significant differences between treatment groups (T2,T3) and control group in the results of previous parameters.The results of histological study showed that there are pathological changes and necrosis in the tissues of liver , kidney , testis and epididymis in a T1 group comared with control group, Whilst treatment groups (T2,T3) were showed clear improvement in the tissues & organs included in local study & correct the damage caused by induced diabetes as a result of treatment with barley and oats.From the above results we concluded that alcoholic extracts of barley & oats have positive role in the improvement of some physiological & histological parameters in the alloxane induced diabetes rats.