Associations between clinical characteristics and angiotensin-converting enzyme gene insertion deletion polymorphism in Moroccan population with type-2 diabetic nephropathy
المؤلفون المشاركون
Mansuri, Maria
Znibir, Amal
Boualla, Lamia
al-Badawi, Ghizlani
Bin Qasim, Maryam
Rifai, Kawthar
Shraibi, Abd al-Majid
Bin Amar, Lubna
Sufyani, Abd al-Aziz
Bayahia, Rabiah
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 28، العدد 2 (30 إبريل/نيسان 2017)، ص ص. 261-267، 7ص.
الناشر
تاريخ النشر
2017-04-30
دولة النشر
السعودية
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Diabetic nephropathy (DN) is one of the severe complications of Type-2 diabetes mellitus (T2DM) and a major cause of end-stage renal disease in these patients.
Results from published studies on the relationship between angiotensin-converting enzyme (ACE) insertion/ deletion (I/D) gene polymorphism and patients with DN are still conflicting.
We compared the clinical characteristics and the genotype frequencies of ACE polymorphism in 130 T2DM Moroccan patients with DN and 85 T2DM Moroccan patients without DN (controls) using specific primers in a polymerase chain reaction.
The degenerative complications of diabetes were significantly higher in the group with nephropathy.
The distribution of the I/D genotypes was in Hardy–Weinberg equilibrium.
The D allele was the most frequent allele in the Moroccan population in both groups studied (P = 0.68), however, there was no significant difference between the genotypes in T2DM patients with or without DN (P = 0.78).
The ACE gene I/D polymorphism was not associated with an increased risk of DN in the Moroccan population.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mansuri, Maria& Znibir, Amal& Boualla, Lamia& al-Badawi, Ghizlani& Bin Qasim, Maryam& Rifai, Kawthar…[et al.]. 2017. Associations between clinical characteristics and angiotensin-converting enzyme gene insertion deletion polymorphism in Moroccan population with type-2 diabetic nephropathy. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 2, pp.261-267.
https://search.emarefa.net/detail/BIM-761836
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mansuri, Maria…[et al.]. Associations between clinical characteristics and angiotensin-converting enzyme gene insertion deletion polymorphism in Moroccan population with type-2 diabetic nephropathy. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 2 (Mar. / Apr. 2017), pp.261-267.
https://search.emarefa.net/detail/BIM-761836
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mansuri, Maria& Znibir, Amal& Boualla, Lamia& al-Badawi, Ghizlani& Bin Qasim, Maryam& Rifai, Kawthar…[et al.]. Associations between clinical characteristics and angiotensin-converting enzyme gene insertion deletion polymorphism in Moroccan population with type-2 diabetic nephropathy. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 2, pp.261-267.
https://search.emarefa.net/detail/BIM-761836
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 265-267
رقم السجل
BIM-761836
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر