Primary sjogren’s syndrome complicated by anti-neutrophil cytoplasmic antibody-mediated crescentic glomerulonephritis

الملخص EN

Ocular and oral dryness are the hallmark of Sjögren’s syndrome (SS).

However, SS can be associated with a variety of complications, affecting organs such as the liver, kidneys, lungs, muscle, and nervous system.

Renal involvement has been usually in the form of tubulointerstitial nephritis.

However, glomerulonephritis is rare in primary SS.

We report three clinical cases of SS with anti-neutrophil cytoplasmic antibody-mediated crescentic glomerulonephritis treated with prednisone and cyclophosphamide, with favorable outcome.