العلاقة بين مستويات الرصاص في الدم و التشوهات الكروموسومية في رجال شرطة المرور في محافظة ذي قار

الملخص EN

The aim of this investigation to determine the relationship between blood lead levels and Chromosome aberrations in traffic police constables in Thi-Qar province.

Blood samples were collected from 27 males traffic police constables, 22 to 45 years of age, posted in different areas of Thi- Qar province, 27 males (13 – 35), residing in comparatively clean and very low traffic areas were included as controls.

Blood lead concentrations were estimated from lymphocyte were made by standardized routine methods.

Statistical analysis of the results showed the mead blood lead level among constables (8.58 µg ̸ 100 ml) was no significant (p˃ 0.05) as compared to controls (3.12 µg ̸ 100 ml).

No correlation was found between blood lead levels and age, length of service, also this study individual that no significant different frequencies of chromosomal aberrations which gave indicator that the lead was not effect in the concentration about (4.2 – 11.7 µg ̸ 100 ml) average (8.58 µg ̸100ml) in the traffic constables.

The aging and period of employment have no effect on the frequency of chromosomal aberration in both group.

Also results a positive interaction between the cigarettes smoking and the exposure to lead during the work have a significant effect on the genetic material (DNA) of lymphocytes, there were structural abnormalities like as acentric chromosomes in traffic police constables