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Relationship between expression of CXCR7 and NF-ĸB in breast cancer tissue and occurrence of breast cancer and lymphatic metastasis
المؤلفون المشاركون
Zou, Ning
Yuan, Cheng Liang
Liu, Zhao Hong
Chen, Zhong Yao
Wang, Ya Li
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 24، العدد 8 (31 ديسمبر/كانون الأول 2017)، ص ص. 1767-1770، 4ص.
الناشر
تاريخ النشر
2017-12-31
دولة النشر
السعودية
عدد الصفحات
4
التخصصات الرئيسية
العلوم الطبيعية والحياتية (متداخلة التخصصات)
الملخص EN
It is designed to discuss the relationship between the expression of chemokine receptor 7 (chemokine receptor 7, CXCR7) and nuclear transcription factor-ĸB (nuclear factor kappa B, NF-ĸB) and the occurrence of the breast cancer and lymphatic metastasis.
Method: 80 samples were excised and confirmed as breast cancer through our hospital pathology from January 2014 to December 2016 and tumor tissues and normal mammary tissues 2 cm from the tumor edges were taken as an experimental group and a control group, respectively.
The method of immunohistochemical is utilized to test the expression of CXCR7 and NF-ĸB in the breast cancer tissue, compared with the para-carcinoma tissue, and analyze its relevance with the clinicopathologic features of the breast cancer tissue, such as tumor size, TNM staging, lymphatic metastasis and other conditions.
Results : both CXCR7 and NF-ĸB were highly expressed in the breast cancer tissue, the positive rate was significantly higher that that of paracancerous normal tissues, and the difference was statistically significant.
And the expressions of CXCR7 and NF-ĸB were related to TNM staging of the breast cancer and lymphatic metastasis and unrelated to the tumor size, age, and expressions of ER, PR and HER2.
Conclusion: both CXCR7 and NF-ĸB are related to the malignant grade of the breast cancer and lymphatic metastasis, which may be regarded as in important indicator to judge the prognosis of the breast cancer and be expected to be the new target of curing part of the breast cancer.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yuan, Cheng Liang& Liu, Zhao Hong& Zou, Ning& Wang, Ya Li& Chen, Zhong Yao. 2017. Relationship between expression of CXCR7 and NF-ĸB in breast cancer tissue and occurrence of breast cancer and lymphatic metastasis. Saudi Journal of Biological Sciences،Vol. 24, no. 8, pp.1767-1770.
https://search.emarefa.net/detail/BIM-780584
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yuan, Cheng Liang…[et al.]. Relationship between expression of CXCR7 and NF-ĸB in breast cancer tissue and occurrence of breast cancer and lymphatic metastasis. Saudi Journal of Biological Sciences Vol. 24, no. 8 (Dec. 2017), pp.1767-1770.
https://search.emarefa.net/detail/BIM-780584
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yuan, Cheng Liang& Liu, Zhao Hong& Zou, Ning& Wang, Ya Li& Chen, Zhong Yao. Relationship between expression of CXCR7 and NF-ĸB in breast cancer tissue and occurrence of breast cancer and lymphatic metastasis. Saudi Journal of Biological Sciences. 2017. Vol. 24, no. 8, pp.1767-1770.
https://search.emarefa.net/detail/BIM-780584
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 1770
رقم السجل
BIM-780584
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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