Altered renal immune complexes deposition in female BWF1 lupus mice following Plasmodium chabaudi infection
المؤلفون المشاركون
Abd al-Maqsud, Mustafa A.
al-Amir, Azza
Abd al-Ghaffar, Fathi M.
Badr, Jamal A.
al-Qurayshi, Salih A.
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 25، العدد 8 (31 ديسمبر/كانون الأول 2018)، ص ص. 1609-1616، 8ص.
الناشر
تاريخ النشر
2018-12-31
دولة النشر
السعودية
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease that has a mysterious relationship with malaria infection.
The current study was designated to compare between the effect of the live and the gamma irradiated Plasmodium chabaudi infection on BWF1 lupus murine model.
A total of 30 female BWF1 mice were randomly divided into three groups (10 mice/- group) as follows: group (I) lupus group (lupus non infected); group (II) live malaria infected group (lupus + live malaria infection); and group (III) irradiated malaria-infected group (lupus + gamma irradiated malaria infection).
Live P.
chabaudi infection was accompanied with a decrease in survival rate and food consumption in comparison to the control group of mice while gamma irradiated P.
chabaudi -infection was unable to do this effect.
Additionally, live P.
chabaudi infection was accompanied with an increased level of proteinuria and increased rate of immune complexes deposition in kidney.
Moreover, infection with live, but not gamma-irradiated P.
chabaudi was accompanied with an increase in nitric oxide (NO), hydrogen peroxide (H2O2), and malondialdehyde (MDA) levels in plasma of lupus mice.
The levels of both total cholesterol and triglycerides in plasma of lupus mice after live P.
chabaudi infection were obviously decreased in comparison to the control group.
On the other hand, gamma-irradiated P.
chabaudi infection resembled the control group.
Our data revealed that infection of lupus mice with live but not gamma-irradiated P.
chabaudi has several histological and biochemical effects.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abd al-Maqsud, Mustafa A.& Abd al-Ghaffar, Fathi M.& al-Amir, Azza& Badr, Jamal A.& al-Qurayshi, Salih A.. 2018. Altered renal immune complexes deposition in female BWF1 lupus mice following Plasmodium chabaudi infection. Saudi Journal of Biological Sciences،Vol. 25, no. 8, pp.1609-1616.
https://search.emarefa.net/detail/BIM-833087
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abd al-Maqsud, Mustafa A.…[et al.]. Altered renal immune complexes deposition in female BWF1 lupus mice following Plasmodium chabaudi infection. Saudi Journal of Biological Sciences Vol. 25, no. 8 (Dec. 2018), pp.1609-1616.
https://search.emarefa.net/detail/BIM-833087
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abd al-Maqsud, Mustafa A.& Abd al-Ghaffar, Fathi M.& al-Amir, Azza& Badr, Jamal A.& al-Qurayshi, Salih A.. Altered renal immune complexes deposition in female BWF1 lupus mice following Plasmodium chabaudi infection. Saudi Journal of Biological Sciences. 2018. Vol. 25, no. 8, pp.1609-1616.
https://search.emarefa.net/detail/BIM-833087
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 1615-1616
رقم السجل
BIM-833087
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر