Association between exposure to beta 2 agonists and corticosteroids and acquiring benign joint hypermobility syndrome among asthmatic patients : a case-control study
المؤلفون المشاركون
Karkasawi, Nailah Mubarak
Diyab, al-Sarah Mutawakkil Abbas
Sulayman, Iman Mutawakkil Ahmad al-Mustafa
Abd Allah, Ayat Abd Allah Hasan
Diyab, Muhammad Abd al-Hadi al-Zubayr
Awad Allah, Tanzil Umar al-Amin
Husayn, Nazik al-Malaikah Ubayd Sayyid Ahmad
المصدر
Sudan Journal of Medical Sciences
العدد
المجلد 12، العدد 4 (31 ديسمبر/كانون الأول 2017)، ص ص. 215-230، 16ص.
الناشر
جامعة أم درمان الإسلامية كلية الطب
تاريخ النشر
2017-12-31
دولة النشر
السودان
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
Background: Beta2 (?2) agonists as relievers and corticosteroids as controllers are the mainstay drugs for asthma treatment.
Benign Joint Hypermobility Syndrome (BJHS) is a connective tissue disorder with musculoskeletal symptoms.
We had examined gthe possible association between the use of ?2 agonists and corticosteroids and acquiring BJHS in asthmatic patients.
Methods: This was a case-control, hospitalbased study including a group of asthmatics who had BJHS (cases), compared with a matched group of asthmatics without BJHS (controls) for the ?2 agonists and corticosteroids past and current pattern of use.
Information was collected by faceto-face interview and clinical examination and from subjects’ medical records using pre-structured questionnaire.
BJHS diagnosis was based on the revised Brighton criteria.
Asthma severity was reflected by a score, which was calculated from the asthma questionnaire.
Comparison of exposure was done by Calculation of Odds Ratio.
Results: Development of BJHS was found to be significantly associated with chronicity of asthma of average duration of 13.2 years, and hence to prolonged use of ?2 agonists and/or corticosteroids (OR 1.019; 95% CI 0.999 - 1.039, P=0.006).
Exposure to ?2 agonist and corticosteroid (87 and 79 cases and controls respectively P=0.05) high asthma score (42.9 ± 9.8 and 40.4 ± 8.3 among cases and controls respectively, P=0.011) were significantly associated with the development of BJHS.
Conclusion: Frequent and prolonged use of ?2 agonists and corticosteroids is significantly associated with acquiring BJHS.
Implying a possibility of changing approach and handling in asthmatics follow up.
Prospective and experimental studies are needed to support the evidence of association.-
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Diyab, al-Sarah Mutawakkil Abbas& Sulayman, Iman Mutawakkil Ahmad al-Mustafa& Abd Allah, Ayat Abd Allah Hasan& Diyab, Muhammad Abd al-Hadi al-Zubayr& Awad Allah, Tanzil Umar al-Amin& Karkasawi, Nailah Mubarak…[et al.]. 2017. Association between exposure to beta 2 agonists and corticosteroids and acquiring benign joint hypermobility syndrome among asthmatic patients : a case-control study. Sudan Journal of Medical Sciences،Vol. 12, no. 4, pp.215-230.
https://search.emarefa.net/detail/BIM-836593
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Diyab, al-Sarah Mutawakkil Abbas…[et al.]. Association between exposure to beta 2 agonists and corticosteroids and acquiring benign joint hypermobility syndrome among asthmatic patients : a case-control study. Sudan Journal of Medical Sciences Vol. 12, no. 4 (2017), pp.215-230.
https://search.emarefa.net/detail/BIM-836593
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Diyab, al-Sarah Mutawakkil Abbas& Sulayman, Iman Mutawakkil Ahmad al-Mustafa& Abd Allah, Ayat Abd Allah Hasan& Diyab, Muhammad Abd al-Hadi al-Zubayr& Awad Allah, Tanzil Umar al-Amin& Karkasawi, Nailah Mubarak…[et al.]. Association between exposure to beta 2 agonists and corticosteroids and acquiring benign joint hypermobility syndrome among asthmatic patients : a case-control study. Sudan Journal of Medical Sciences. 2017. Vol. 12, no. 4, pp.215-230.
https://search.emarefa.net/detail/BIM-836593
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 228-230
رقم السجل
BIM-836593
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر