Studying the ameliorative effect of bee venom against damage and inflammation induced in gamma-irradiated rats

المؤلفون المشاركون

Hamzah, R. G.
al-Shahat, A. N.
Munir, Ashraf M.

المصدر

Arab Journal of Nuclear Sciences and Applications

العدد

المجلد 52، العدد 1 (31 يناير/كانون الثاني 2019)، ص ص. 178-184، 7ص.

الناشر

الجمعية المصرية للعلوم النووية و تطبيقاتها

تاريخ النشر

2019-01-31

دولة النشر

مصر

عدد الصفحات

7

التخصصات الرئيسية

الأحياء

الموضوعات

الملخص EN

The aim of this study was focused on investigating the possible protective effect of Bee Venom (BV) against gamma radiation induced damage and inflammation in male rats.

Gamma-irradiation (6 Gy) resulted in a significant elevation in the level of tumor necrotic factor-alpha (TNF-α) , interleukin-6 (IL-6) , creatinine kinase-MB (CK-MB) and cardiac troponin I (cTnI), lactate dehydrogenase (LDH), creatine phosphokinase (CPK), serum aspartate transaminase (AST) and alanine transaminase (ALT) , serum glucose, malondialdehyde (MDA) concentration and xanthine oxidase activity associated with remarkable decrease in insulin level, glutathione content (GSH) and the activity of xanthine dehydrogenase (XDH), superoxide dismutase (SOD) and catalase (CAT) in heart and liver tissues compared to control group.

Injection of BV (5ml/kg b.

wt.

/ day/6weeks) to γ-irradiated rats was found to offer protection against γ-irradiation induced oxidative stress and significantly ameliorated the changes occurred in the above investigated biochemical parameters.

It could be concluded that Bee venom clarified a modulatory role against gamma radiation induced oxidative damage and inflammation in the heart and liver tissues.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Hamzah, R. G.& Munir, Ashraf M.& al-Shahat, A. N.. 2019. Studying the ameliorative effect of bee venom against damage and inflammation induced in gamma-irradiated rats. Arab Journal of Nuclear Sciences and Applications،Vol. 52, no. 1, pp.178-184.
https://search.emarefa.net/detail/BIM-880517

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Hamzah, R. G.…[et al.]. Studying the ameliorative effect of bee venom against damage and inflammation induced in gamma-irradiated rats. Arab Journal of Nuclear Sciences and Applications Vol. 52, no. 1 (Jan. 2019), pp.178-184.
https://search.emarefa.net/detail/BIM-880517

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Hamzah, R. G.& Munir, Ashraf M.& al-Shahat, A. N.. Studying the ameliorative effect of bee venom against damage and inflammation induced in gamma-irradiated rats. Arab Journal of Nuclear Sciences and Applications. 2019. Vol. 52, no. 1, pp.178-184.
https://search.emarefa.net/detail/BIM-880517

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references : p. 182-184

رقم السجل

BIM-880517