Evaluation and correlation of hepcidin-25 hormone, hemoglobin and packed cell volume of patients with β-thalassaemia intermedia before and after blood transfusion for iraqi children patients

المؤلفون المشاركون

Sadun, Muhammad K.
Ali, Bushra H.

المصدر

Ibn al-Haitham Journal for Pure and Applied Science

العدد

المجلد 31، العدد 3 (31 ديسمبر/كانون الأول 2018)، ص ص. 70-78، 9ص.

الناشر

جامعة بغداد كلية التربية ابن الهيثم

تاريخ النشر

2018-12-31

دولة النشر

العراق

عدد الصفحات

9

التخصصات الرئيسية

الكيمياء

الملخص EN

P-thalassaemia consists of 3 chief forms: thalassaemia primary (other called "cooley's Anaemia" or "Mediterranean durability Anaemia”), thalassaemia intermedia or thalassaemia minor also frequent termed "P-thalassaenna carrier", "P-thalassaemia trait" however, "heterozygous P-thalassaemia".

separately from the rare magisterial forms, problem along P- thalassaemia essential are komozygotes or made heterozygotes because B° and B~ genes, problem including thalassaemia intermedia are typically homozygotes and compound heterozygotes then subjected with thalassaemia minor are broadly heterozygotes.

In this study, we take eighty humans the age about them had been mean=SD (9.68=2.08).

40 patients along P-thalassaemia intermedia, then 40 healthy people as much control, extraction gore 5ml from thalassaemia's patients before gore transfusion then afterwards take the blood by way of three days.

The samples we instituted are 120.

forty samples before blood transfusion.

40 samples after gore transfusion then 40 control samples.

Then we separated every pattern of twin's tubes.

Amplify blood attention about P-thalassaenua intermedia patient since blood advancement due according to minimize degree regarding hepcidin-25 further than its instruction was once shown up iron focus meanly affect through hepcidin-25 level, therefore so hepcidin-25 used to be surprisingly significant exchange in P- thalassaemia intermedia affected person afterwards blood advancement yet so much conduct to iron overload.

So we conclude low level of Hemoglobin before and after blood transfusion due to decrease or absent formation of P-globin that because gene disorder, and conclude correlation between kepcidin hormone with Hb and PCV.

The aim of this study is to evaluate hepcidin-25 levels, hemoglobm [Hb] and packed cell volume [PCV] before and after blood transfusion, then correlation of hepcidin-25 hormone with [Hb] and [PCV] of children patients with P-thalassaemia intermedia.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Sadun, Muhammad K.& Ali, Bushra H.. 2018. Evaluation and correlation of hepcidin-25 hormone, hemoglobin and packed cell volume of patients with β-thalassaemia intermedia before and after blood transfusion for iraqi children patients. Ibn al-Haitham Journal for Pure and Applied Science،Vol. 31, no. 3, pp.70-78.
https://search.emarefa.net/detail/BIM-900651

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Sadun, Muhammad K.& Ali, Bushra H.. Evaluation and correlation of hepcidin-25 hormone, hemoglobin and packed cell volume of patients with β-thalassaemia intermedia before and after blood transfusion for iraqi children patients. Ibn al-Haitham Journal for Pure and Applied Science Vol. 31, no. 3 (2018), pp.70-78.
https://search.emarefa.net/detail/BIM-900651

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Sadun, Muhammad K.& Ali, Bushra H.. Evaluation and correlation of hepcidin-25 hormone, hemoglobin and packed cell volume of patients with β-thalassaemia intermedia before and after blood transfusion for iraqi children patients. Ibn al-Haitham Journal for Pure and Applied Science. 2018. Vol. 31, no. 3, pp.70-78.
https://search.emarefa.net/detail/BIM-900651

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references : p. 76-78

رقم السجل

BIM-900651