فحص حساسية عزلات جرثومة Acinetobacter baumannii و التحري عن فئة الجينات التابعة ل blaoxa و adeABC المسؤولة عن مقاومة المضادات الحيوية

العناوين الأخرى

Sensitivity testing of Acinetobacter baumannii and detection of some resistance genes affiliate of blaoxa and adeABC

المؤلفون المشاركون

دينا نوفل وجيه
شكيبة يونس شريف
النعمان، أديبة يونس شريف حمو

المصدر

Rafidain Journal of Science

الناشر

جامعة الموصل كلية العلوم

تاريخ النشر

2018-10-31

دولة النشر

العراق

عدد الصفحات

13

التخصصات الرئيسية

الأحياء

الملخص الإنجليزي

Eight isolates of Acinetobacter baumannii showed absolute resistance (100 %) to Ampicillin, Ceftriaxone, Ciprofloxacin, Cefotaxime, Gentamicin, Piperacillin, Ticarcillin, Trimethoprim-sulfamethoxazol, while it showed moderate resistance (50 %) to Tobramycin and low resistance to each of Amikacin and Netillin (37.5 %).

For the detection of the causes of resistance blaoxa51 genes, blaoxa53 genes were detected at a rate of 100 % and 87.5 % respectively, while the gene blaoxa58 was not detected in all A.baumannii isolates which confirmed its resistance to B-lactam antibiotics, the results also confirms the presence of the gene adeB which plays role in efflux pump mode of resistance as well as the regulatory genes of adeR and adeS of which their presence confirm the bacterial resistance to antibiotics.

The results showed that the resistance of A.baumannii to B-lactam and Carbapenem antibiotics were mediated by blaoxa23, blaoxa51 and the role of AdeABC was restricted due to the absence of the AdeS regulatory gene from most isolates.

نوع البيانات

أوراق مؤتمرات

رقم السجل

BIM-901907

• APA
• MLA
• AMA