نموذج أولي باستخدام المنطق العائم في الماتلاب لدراسة التوزع الحراري و التحكم به في الأنسجة في أثناء علاج الأورام السرطانية بالتسخين

الملخص EN

Cancer treatment is one of the most subjects treated in medical research.

Many of these researches emphasize that the conventional treatments such as chemotherapy or radiation do not provide satisfactory results in addition to their harmful side effects, therefore it is necessary to work on improving these methods and increase its effectiveness by integrated it with other approaches such as the hyperthermia treatment method.

This work aims to develop a prototype model to study the distribution of temperature and control it in the tissue when it is heated by one of the heating techniques as ultrasound or electromagnetic waves, during the treatment of cancerous tumors in order to replace currently used temperature measurement method, namely to a magnetic resonance which constitute the largest obstacle to the application of hyperthermia treatment technique widely because of its high cost and low accuracy.

A heating control mechanism was performed based on the fuzzy logic to ensure that the tissues adjacent to the tumor not damaged and delivery sufficient thermal energy to the tumor.

A simulation was performed for the work of this system and the control mechanism under various conditions and forms of tumor in order to ensure the effectiveness of the control and system in general and the ability to include it in any future design on the reality.

Good results have been achieved in terms of effectiveness, where the controller succeeded in maintaining the temperature of adjacent tissue of the tumor in the range of normal values, while it increased the temperature of cells inside the tumor to 44 oC, which is a sufficient degree to kill the cell or to increase the toxicity inside the cell, which in turn increases the performance of radiation- and chemotherapy.

The results emphasize that continue researching in hyperthermia therapy alone or in conjunction with radiation- and chemotherapy is valuable to reach the largest possible toxicity of the cells using a lower radiation or chemical dose.