Cytokine Expression in CD3+ Cells in an Infant with Food Protein-Induced Enterocolitis Syndrome (FPIES): Case Report
المؤلفون المشاركون
Barni, S.
Novembre, E.
Cianferoni, A.
Pucci, N.
Mori, F.
de Martino, M.
المصدر
Journal of Immunology Research
العدد
المجلد 2009، العدد 2009 (31 ديسمبر/كانون الأول 2009)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2009-11-17
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated food allergy characterized by severe vomiting, diarrhea, and often failure to thrive in infants.
Symptoms typically resolve after the triggering food-derived protein is removed from the diet and recur within few hours after the re-exposure to the causal protein.
The diagnosis is based on clinical symptoms and a positive food challenge.
In this study, we report a case of FPIES to rice in an 8-month-old boy.
We performed a double-blind placebo-controlled food challenge (DBPCFC) to rice and we measured the intracellular T cell expression of interleukin-4 (IL-4); IL-10, and interferon γ (IFN-γ) pre-and post-challenge during an acute FPIES reaction and when tolerance to rice had been achieved.
For the first time we describe an increase in T cell IL-4 and decrease in IFN-γ expression after a positive challenge with rice (i.e.
rice triggered a FPIES attack) and an increase in T cell IL-10 expression after rice challenge 6 months later after a negative challenge (i.e., the child had acquired tolerance to rice) in an 8 month old with documented FPIES to rice.
A Th2 activation associated with high IL-4 levels may contribute to the pathophysiology of the disease.
On the other hand, T cell-derived IL-10 may play a role in the acquisition of immunotolerance by regulating the Th1 and Th2 responses.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mori, F.& Barni, S.& Cianferoni, A.& Pucci, N.& de Martino, M.& Novembre, E.. 2009. Cytokine Expression in CD3+ Cells in an Infant with Food Protein-Induced Enterocolitis Syndrome (FPIES): Case Report. Journal of Immunology Research،Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-988619
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mori, F.…[et al.]. Cytokine Expression in CD3+ Cells in an Infant with Food Protein-Induced Enterocolitis Syndrome (FPIES): Case Report. Journal of Immunology Research No. 2009 (2009), pp.1-4.
https://search.emarefa.net/detail/BIM-988619
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mori, F.& Barni, S.& Cianferoni, A.& Pucci, N.& de Martino, M.& Novembre, E.. Cytokine Expression in CD3+ Cells in an Infant with Food Protein-Induced Enterocolitis Syndrome (FPIES): Case Report. Journal of Immunology Research. 2009. Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-988619
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-988619
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر