Potential effect of milk thistle (silybum marianum)‎ on liver disorders induced by carbon tetrachloride

Abstract EN

This study was conducted to investigate the effect of milk thistle on rats with induced by carbon tetrachloride Thirty mature albino rats weighting 150-160 gm B.

wt.

each were used, and divided into 6 equal groups, one was kept as a control (- ve) group, while the other groups were injected s/c by (0.2 ml/kg) carbon tetrachloride twice a week for Two weeks.

The used plants were given as a percent of 0.5% , 1% , 1.5% and 2% from the basel diet.

, Serum liver function (AST, ALT and ALP), total cholesterol and triglycerides, lipoproteins (HDL-c, LDL-c, VLDL-c) were determined kidney functions (urea, creatinine, uric acid).

The obtained results concluding that feeding with milk thistle herb improved, liver functions, kidney functions and lipid profile.