A comparative study of nano magnesium oxide versus platelets rich fibrin to repair the induced radial fracture in dogs

Abstract EN

This project evaluated the effects of NANO magnesium oxide versus platelets rich fibrin on induced radial fracture bone healing.

eighteen males and non-pregnant females of adult local stray dogs, weighing 17.6 ± 0.8 kg and aged 2.0 ± 0.1 years, were used.

these trials animals were randomly divided into three groups of equal numbers.

in the first group, control group (C), a transverse radial fracture was induced then immobilized by external fixation as gypsum.

in this group, the fracture line was not treated with any bioactive material.

in the second group, platelets rich fibrin group (PRF), the fracture line was treated by adding platelets rich fibrin.

in the third group, NANO magnesium oxide (NMO), the fracture line was treated by adding a suspension of NANO magnesium oxide.

the radiographic results showed that the fractured bone healing was faster in the second group than in the first and third groups, while the third group was better than the first group.

the concentration rates of serum calcium and alkaline phosphatase were increased in the weeks followed the surgical operation.

depending on the radiographic pictures and serial rates of alkaline phosphatase, the second PRF and the third NMO groups were the better-fractured bone healing than the first one.

in conclusion, this study revealed that using each platelets rich fibrin and NANO magnesium oxide enhanced and improved the healing of the induced radial fracture.