Detecting phenotypic and genotypic of the antibiotic resistant salmonella enterica serotype paratyphi isolated from blood samples in Najaf province-Iraq
Joint Authors
al-Muhannak, Fadil Husayn Nasir
al-Shiri, Hashim Ali Abd al-Amir
Abd al-Sadah, Ibrahim Abd al-Ali
Mahmud, Dhikra Abd Allah
Ubayd, Rasha Fadil
Source
Issue
Vol. 18, Issue 2 (31 Dec. 2022), pp.98-106, 9 p.
Publisher
University of Kufa Faculty of Medicine
Publication Date
2022-12-31
Country of Publication
Iraq
No. of Pages
9
Main Subjects
Abstract EN
Background & Objectives: Salmonella Paratyphi is a leading cause of human paratyphoid fever in developing countries, causing deaths in humans worldwide.
There are several paths for catching paratyphoid fever, but the close contact between patients and healthy humans is so far the most frequent cause of human infections.
No study is found about the antibiotic resistance (phenotypic and genetic) of S.
Paratyphi isolated from patients in Al-Najaf Province/Iraq, to the researcher’s best knowledge.
Hence, this study aimed to determine the prevalence of S.
Paratyphi isolates from blood specimens and the antibiotic resistance determinants of them, as well as the genetic relationship among isolates.
Methods and Results: Blood specimens from 1743 patients with suspected enteric fever were cultured for the identification of Salmonella enterica during the period from first April to the end of October 2017.
107 (6.14%) S.
enterica isolates were recovered and only two (1.87%) of isolates were S.
enterica serovar Paratyphi B.
These two isolates (ST39 and ST89) were tested against 23 antibiotics using the disc diffusion method on Muller-Hinton agar and the genotypic antibiotic resistance determinants by PCR.
ST39 isolate was sensitive to all antibiotics while ST89 isolate was resistant to only cefepime, piperacillin and tobramycin.
ST39 isolate did not carry integrons (1 or 2) and any resistance determinants, while ST89 isolate carried integron class1 as well as blaTEM, blaCTX-M and aac(6')-lb genes.
Conclusions: The findings of S.
Paratyphi isolates with integron 1 and resistant antibiotic genes indicating public health risks.
American Psychological Association (APA)
al-Muhannak, Fadil Husayn Nasir& al-Shiri, Hashim Ali Abd al-Amir& Abd al-Sadah, Ibrahim Abd al-Ali& Mahmud, Dhikra Abd Allah& Ubayd, Rasha Fadil. 2022. Detecting phenotypic and genotypic of the antibiotic resistant salmonella enterica serotype paratyphi isolated from blood samples in Najaf province-Iraq. Kufa Medical Journal،Vol. 18, no. 2, pp.98-106.
https://search.emarefa.net/detail/BIM-1494086
Modern Language Association (MLA)
al-Muhannak, Fadil Husayn Nasir…[et al.]. Detecting phenotypic and genotypic of the antibiotic resistant salmonella enterica serotype paratyphi isolated from blood samples in Najaf province-Iraq. Kufa Medical Journal Vol. 18, no. 2 (Dec. 2022), pp.98-106.
https://search.emarefa.net/detail/BIM-1494086
American Medical Association (AMA)
al-Muhannak, Fadil Husayn Nasir& al-Shiri, Hashim Ali Abd al-Amir& Abd al-Sadah, Ibrahim Abd al-Ali& Mahmud, Dhikra Abd Allah& Ubayd, Rasha Fadil. Detecting phenotypic and genotypic of the antibiotic resistant salmonella enterica serotype paratyphi isolated from blood samples in Najaf province-Iraq. Kufa Medical Journal. 2022. Vol. 18, no. 2, pp.98-106.
https://search.emarefa.net/detail/BIM-1494086
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 105-106
Record ID
BIM-1494086