The relationship between lipid profile and inflammatory markers in patients with early rheumatoid arthritis
Joint Authors
Muhammad, Layla Ali
Mahdi, Ilham Ubayd
Hadi, Muna Abbas
Source
Iraqi National Journal of Chemistry
Issue
Vol. 2012, Issue 47 (30 Sep. 2012), pp.391-400, 10 p.
Publisher
University of Babylon College of Sciences
Publication Date
2012-09-30
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Topics
Abstract AR
الالتهاب المفصلي الروماتویدي المعروف باسم الروماتوید یطلق علیه أیضا الالتهاب المفصلي الرثواني الذي یقترن مع فقدان الحیاة إذا ما أصیب المریض بتصلب الشرایین أو الجلطة الناتجة من ترسب الدهون في الأوعیة الدمویة و انسدادها . صممت هذه الدراسة للتحقق فیما إذا كانت هناك علاقة بین فعالیة المرض و مستویات أشكال الدهون المختلفة لدى مرضى التهاب المفاصل الرثوي في المرحلة المبكرة من المرض قبل أن یتعاطوا أي علاج.
تضمنت الدراسة 35 مریض من الذین یراجعون مدینة الصدر الطبیة في محافظة النجف الأشرف، تم مقارنة نتائجهم مع 45 من الأصحاء. أوضحت الدراسة أن هناك علاقة ارتباطیة معنویة بین انخفاض (HDLC) مع ارتفاع كل من ESR و CRP <0.005))، (<0.0001) على التوالي.
یقترن ارتفاع الكولیستیرول الكلي (TC) مع ارتفاع كل من ESR و CRP (p<0.0001)، (p<0.0005) على التوالي كذلك ارتفاع (LDLC) له علاقة بارتفاع كل من ESR و CRP (<.0001)، <0.05)) على التوالي، لوحظ أیضا أن هناك علاقة غیر معنویة بین ارتفاع (TG) مع ESR و علاقة إيجابية بين (TG) المصلي و CRP.
Abstract EN
Rheumatoid arthritis is associated with an excess mortality from cardiovascular disease(CVD) and this may be related to an atherogenic lipid profile.
This study was designed to identify whether there was a correlation between disease activity and levels of different lipid fractions in early rheumatoid arthritis (ERA) before used any treatment.
Thirty fife of ERA patients who met in Al-Sader medical city were included in the study compared results with Forty fife apparently healthy individuals.
In the present study significant relationship exists between reduced high density lipoprotein –cholesterol (HDLC) and elevated C-reactive protein (CRP) p value was (<0.0001) and elevated erythrocyte sedimentation rate (ESR) p value was (<0.005).Raised of total cholesterol (TC) was associated with raised of both ESR and CRP (<0.0001), (<0.0005) respectively.
A significant relationship is demonstrated between elevated ESR and CRP with raised low density lipoprotein –cholesterol (LDLC) (p<0.0001) and (p<0.05) respectively.
Non significant correlation of ESR with raised triglycerides (TG) but significant correlation between CRP and serum TG.
American Psychological Association (APA)
Mahdi, Ilham Ubayd& Muhammad, Layla Ali& Hadi, Muna Abbas. 2012. The relationship between lipid profile and inflammatory markers in patients with early rheumatoid arthritis. Iraqi National Journal of Chemistry،Vol. 2012, no. 47, pp.391-400.
https://search.emarefa.net/detail/BIM-316222
Modern Language Association (MLA)
Mahdi, Ilham Ubayd…[et al.]. The relationship between lipid profile and inflammatory markers in patients with early rheumatoid arthritis. Iraqi National Journal of Chemistry No. 47 (Sep. 2012), pp.391-400.
https://search.emarefa.net/detail/BIM-316222
American Medical Association (AMA)
Mahdi, Ilham Ubayd& Muhammad, Layla Ali& Hadi, Muna Abbas. The relationship between lipid profile and inflammatory markers in patients with early rheumatoid arthritis. Iraqi National Journal of Chemistry. 2012. Vol. 2012, no. 47, pp.391-400.
https://search.emarefa.net/detail/BIM-316222
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 400
Record ID
BIM-316222