Synthesis and identification of schiff bases and bilogical activity new study

Abstract EN

In this work we focused on the synthesis of new Open Schiff bases which were prepared by condensation of salicylaldehyde with both 4, 4'-diaminodiphenyl methane, 4, 4'-diamino diphenyl sulphide, and by condensation of O-vanilin with diethyl ester of terephthalic acid respectively.

Also new macro cyclic Schiff Bases were prepared by condensation of 1, 6-bis (2-formylphenyl) hexane with thiocarbohydrazid.

The Schiff bases were checked by different spectral technique (LC-MS, 1H-NMR, IR).

The work was extended to study the effect of the prepared compounds on four different bacteria in order to test their biological activity.