Clinical study of cutaneous drug eruptions

Abstract EN

Cutaneous drug eruptions have become very common in recent times.

they are the most common adverse reactions attributed to drugs . Objective : To verify the clinical pictures of allergic skin cases and the identifying the causative drugs. Methods : A study of 50 cases of skin drug eruption resulting from drug administration who attended the consultation clinic of dermatology in ASl-Sadr Hospital in Najaf for the period from January 2006 to January 2008 .The diagnosis depended on the full history and clinical examination including standard case criteria . The diagnosis was confirmed by withdrawal of the drug and notifying the disappearance of the skin eruptions and clinical picture of the skin allergy that was resulted from the drug administration. Results : The study included fifty patients;28 males and 22 females. Most of cases were found in age group 41-50 .

The most frequent skin allergic reaction was the fixed drug eruption (30 % of cases).

The drugs which were frequently caused eruptions included ; nonsteroidal anti-inflammatory (21 %), and Cotrimoxazol (14 %) of total cases. Conclusion : All drugs may cause drug eruptions and have to be considered when prescribed to the patients.