Anti obesity and lipid-lowering effect of Lactobacillus Spp. as probiotic on the obese rat

Abstract EN

The effects of Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus casi and Lactobacillus rhomunas on the body weight and lipid metabolism on obese rats were evaluated.

In the body weight, the results showed significant deference between rat groups, the group that consumed 3 probiotic strains showed reduction in the body weight with ratio 16.63 % while the group consumed 2 probiotic strains showed decreasing with ratio 17.62 % compared with control group which increased in the body weight.In the effeci of probiotics on lipid metabolisim the results showed significant deference between rat groups, the group that consumed 3 probiotic strains showed decreasing in the cholesterol with ratio 50.7 %, triglyceride with ratio 48.8 %, LDL with ratio 51 % and elevated of HDL level with ratio 45 %, while the group consumed the 2 probiotic strains showed decreasing in the cholesterol with ratio 48.3 %, triglyceride with ratio 43.3 %, LDL with ratio 27.4 % and elevated HDL level with ratio 26 %.

The study suggests that LAB supplementation has hypocholesterolemic and anti-obesity effects in rats.

These strains might be able to improve the intestinal microbial balance and potentially improve intestinal transit time.