مقاومة بعض العصيات المعوية السالبة لصبغة كرام المعزولة من إصابات الجهاز التنفسي السفلي لمضادات البيتا-لاكتام

Abstract EN

One hundred and four isolates of gram negative enteric bacilli were isolated from (700) sputum specimens taken from lower respiratory tract infections with isolation percentage of (14.8 %).

The bacterial isolates belonged to the species : Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Enterobacter aerogenes, Enterobacter cloacae, Serratia marcescens, Proteus mirabilis, with variable isolation percentages.

The isolates showed an obvious resistance to different β-lactam antibiotics including third generation cephalosporins, where the resistance percentages to Cefixime, Cefotaxime, Ceftazidime reached (52.9 %), (51.9 %), (42.3 %) respectively, they also showed resistance to Cefoxitin (31.7 %), while Cefepime, Meropenem, Imipenem had a high activity against the isolates, as the resistance rates were reduced to reach (8.7 %), (1.9 %), (1.0 %) respectively.

Ps.

aeruginosa isolates were the most resistant species to β-lactams, followed by K.

pneumoniae isolates, while Pr.

mirabilis isolates were the most susceptible ones.