Anticancer activity of sunflower (Helianthus annuns L.) seeds oil against cell lines
Other Title(s)
فعالية زيت بذور زهرة الشمس (Helianthus annuns L.) ضد الخطوط الخلوية السرطانية
Joint Authors
al-Shamma, Layth Muhammad Jawad
al-Jumayli, Rakkad Muhammad Khammas
al-Halbusi, Muhammad Mahmud Farhan
al-Shamma, Nawal Muhammad Jawad
Source
Issue
Vol. 54, Issue 4 (sup) (31 Dec. 2013), pp.1003-1009, 7 p.
Publisher
University of Baghdad College of Science
Publication Date
2013-12-31
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Topics
Abstract AR
تهدف هذه الدراسة إلى التحري عن التأثيرات السمية الخلوية لزيت بذور زهرة الشمس (Helianthus annus L.) في اثنين من الخطوط الخلوية RD و L20B باستخدام ثمانية تراكيز مختلفة 1.3، 2.6، 5.2، 10.4، 20.8، 41.6، 83.2، 166.4مايكروغرام / مللتر و ضمن فترة تعريض مختلفة (23، 48 و 72 ساعة).
أظهرت النتائج وجود تأثير سمي واضح و بمعنوية عالية لمستخلص زيت بذور زهرة الشمس في نمو الخط الخلوي السرطاني RD، علما أن نسبة زادت بزيادة و سجل أعلى تأثير تثبيطي في نمو الخط الخلوي السرطاني RD لتركيز 83.2 و 166.4 خلال فترة تعريض 24 و 72 ساعة مقارنة بالسيطرة.
في حين لم يكن هناك تأثير واضح للمستخلص بذور زيت زهرة الشمس في نمو الخلايا المتحولة L20B.
Abstract EN
This study investigated the role of sunflower (Helianthus annuns L.) seed extracts as a cytotoxic agent against two cell lines (RD and L20B) using different concentrations of sunflower seeds oil 1.3 , 2.6 , 5.2, 10.4 , 20.8, 41.6 , 83.2 and 166.4 μg / ml for different exposure time (24 ,48 and 72 hrs).
The results revealed a clear cytotxoic activity of sunflower seeds oil on growth of RD cancer cell line, and the effect was concentration-dependent.
The signification inhibition (P<0.05) was obtained at a concentration of 83.5 and 166.4 μg / ml as compared to control.
In addition, the growth of RD cell line was more sensitive to sunflower seeds oil in comparison with the growth of L20B transform cell line.
In conclusion, the extract showed inhibitory effect on cancer cell line and it is promising to use as anticancer drug.
American Psychological Association (APA)
al-Jumayli, Rakkad Muhammad Khammas& al-Shamma, Nawal Muhammad Jawad& al-Halbusi, Muhammad Mahmud Farhan& al-Shamma, Layth Muhammad Jawad. 2013. Anticancer activity of sunflower (Helianthus annuns L.) seeds oil against cell lines. Iraqi Journal of Science،Vol. 54, no. 4 (sup), pp.1003-1009.
https://search.emarefa.net/detail/BIM-352245
Modern Language Association (MLA)
al-Jumayli, Rakkad Muhammad Khammas…[et al.]. Anticancer activity of sunflower (Helianthus annuns L.) seeds oil against cell lines. Iraqi Journal of Science Vol. 54, no. 4 (Supplement) (2013), pp.1003-1009.
https://search.emarefa.net/detail/BIM-352245
American Medical Association (AMA)
al-Jumayli, Rakkad Muhammad Khammas& al-Shamma, Nawal Muhammad Jawad& al-Halbusi, Muhammad Mahmud Farhan& al-Shamma, Layth Muhammad Jawad. Anticancer activity of sunflower (Helianthus annuns L.) seeds oil against cell lines. Iraqi Journal of Science. 2013. Vol. 54, no. 4 (sup), pp.1003-1009.
https://search.emarefa.net/detail/BIM-352245
Data Type
Journal Articles
Language
English
Notes
Text in English ; abstracts in English and Arabic.
Record ID
BIM-352245
