Histopathological changes and metabolic gene polymorphism caused by aramite exposure in experimental rats
Other Title(s)
التغيرات النسيجية المرضية و التعدد و الوراثي الناجمة عن التعرض للأراميت في الجرذان المختبرية
Joint Authors
al-Badran, Adnan Isa
al-Sari, Majid Husayn Majid
al-Qurayshi, khatam Jasim Salih
Source
Journal of Basrah Researches : Sciences
Issue
Vol. 35, Issue 2A (30 Apr. 2009)18 p.
Publisher
University of Basrah College of Education for Pure Sciences
Publication Date
2009-04-30
Country of Publication
Iraq
No. of Pages
18
Main Subjects
Topics
Abstract AR
مجموع 40 جرذ مختبري نوع Rattys.
Norvegicus قد قسمت إلى ثلاث مجاميع تمثلت ب G1 (10 جرذان) كمجموعة سيطرة و G2 (15 جرذان) عرضت للاراميت مع الغذاء لمدة 90 يوم بتركيز (5 غم \ 1 كغم عليقة) و G3 (15 جرذان) عرضت للاراميت مع الماء لمدة 90 يوم بتركيز (5 غم \ 1 لتر ماء الحنفية).
أظهرت النتائج بحصول زيادة معنوية في مستوى خماير GPT, GOT, ACP و ALP في المجاميع المعاملة بالاراميت مقارنة مع مجموعة السيطرة.
كذلك أظهرت الدراسة النسيجية حصول تغيرات نسيجية مرضية في الكبد و الأمعاء و طفرات وراثية واضحة في جين GSTMI في المجاميع المعاملة بالاراميت مع الغذاء و الماء مقارنة مع مجموعة السيطرة.
Abstract EN
A total of 40 experiment rats ( Rattus norvegicus) were divided into three groups of 10 rats for G.1 normal rats; 15 rat for G.2 that exposed to aramite with food daily for 90 days (5 g aramite/1 kg of pellet diet) and 15 rat for G.3 that exposed to aramite with water daily for 90 days(5 g aramite dissolved in 1 litter tap water The result shows that the rats that were treated with aramite suffer from significant increased the activity and level of GPT; GOT ; ACP and ALP (P≤0.05) compared with control group , so the results fixed the histopathological changes in liver and intestine with clear mutation in GSTM1 gene in rats that were exposed to aramite with diet and water compared with the normal control rats.
American Psychological Association (APA)
al-Badran, Adnan Isa& al-Sari, Majid Husayn Majid& al-Qurayshi, khatam Jasim Salih. 2009. Histopathological changes and metabolic gene polymorphism caused by aramite exposure in experimental rats. Journal of Basrah Researches : Sciences،Vol. 35, no. 2A.
https://search.emarefa.net/detail/BIM-382116
Modern Language Association (MLA)
al-Badran, Adnan Isa…[et al.]. Histopathological changes and metabolic gene polymorphism caused by aramite exposure in experimental rats. Journal of Basrah Researches : Sciences Vol. 35, no. 2A (Apr. 2009).
https://search.emarefa.net/detail/BIM-382116
American Medical Association (AMA)
al-Badran, Adnan Isa& al-Sari, Majid Husayn Majid& al-Qurayshi, khatam Jasim Salih. Histopathological changes and metabolic gene polymorphism caused by aramite exposure in experimental rats. Journal of Basrah Researches : Sciences. 2009. Vol. 35, no. 2A.
https://search.emarefa.net/detail/BIM-382116
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-382116