Apoptosis and necrosis levels in chemotherapy treated chronic lymphocytic leukemia patients
Other Title(s)
مستوى الاستماتة و التنخر عند مرضى ابيضاض الدم المزمن المقاومين للعلاج الكيميائي
Joint Authors
al-Faysal, Abd al-Husayn Muwayt
Abd al-Hasan, Manal Laftah
Source
Iraqi Journal of Biotechnology
Issue
Vol. 13, Issue 1 (30 Jun. 2014), pp.39-45, 7 p.
Publisher
University of Baghdad Genetic Engineering and Biotechnology for Postgraduate Studies
Publication Date
2014-06-30
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Topics
Abstract AR
بينت النتائج أن المعالجة الكيميائية لمرضى ابيضاض الدم المزمن أدت إلى زيادة تعبير الموزث و ذلك من خلال قياس مستوى الفوسفوتايدل سيرين و الذي أدى إلى زيادة نسبة الاستماتة و التثخر.
بينت النتائج أيضاً أن نسبة التنخر كانت عالية معنوياً عند مجموعة المرضى (1.07, 0.03) مقارنة مع الأصحاء (0.17, 0.02) و عدم وجود فرق معنوي بينهما في حيوية الخلايا (86.8% و 82.88% على التوالي).
كما أن نسبة الخلايا المستماتة كانت عالية معنوياً أيضاً عند المرضى مقارنة (0.15.04, 1.03) مع الأصحاء (4.40,0.5) بينما كانت الاستماتة المتأخرة غير معنوية بينهما (0.638, 0.803% على التوالي).
Abstract EN
The results showed that CLL patients chemotherapy treatment increase the expression of Bcl2 gene (via measuring the phosphatidylserine -PS level) which increased apoptosis and necrosis percentage.
It is also showed that the Necrotic cells (%) were found to be significantly higher in patients samples (1.07 ± 0.03) than in healthy (0.17 ± 0.02) with no significance in viable cells (%) (82.88 % in patients and 86.8 % in healthy).
The apoptotic cells % were found to be significantly higher in patients (15.04 ± 1.03) than healthy (4.40 ± 0.5).
On the other hand, late apoptosis % showed no significant results (0.639 % in patients and 0.803 % in healthy).
American Psychological Association (APA)
al-Faysal, Abd al-Husayn Muwayt& Abd al-Hasan, Manal Laftah. 2014. Apoptosis and necrosis levels in chemotherapy treated chronic lymphocytic leukemia patients. Iraqi Journal of Biotechnology،Vol. 13, no. 1, pp.39-45.
https://search.emarefa.net/detail/BIM-388966
Modern Language Association (MLA)
al-Faysal, Abd al-Husayn Muwayt& Abd al-Hasan, Manal Laftah. Apoptosis and necrosis levels in chemotherapy treated chronic lymphocytic leukemia patients. Iraqi Journal of Biotechnology Vol. 13, no. 1 (2014), pp.39-45.
https://search.emarefa.net/detail/BIM-388966
American Medical Association (AMA)
al-Faysal, Abd al-Husayn Muwayt& Abd al-Hasan, Manal Laftah. Apoptosis and necrosis levels in chemotherapy treated chronic lymphocytic leukemia patients. Iraqi Journal of Biotechnology. 2014. Vol. 13, no. 1, pp.39-45.
https://search.emarefa.net/detail/BIM-388966
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 44-45
Record ID
BIM-388966
