Spectrophotometric determination of mefenamic acid in pharmaceutical preparations
Other Title(s)
التقدير الطيفي لعقار حامض الميفيناميك في مستحضراته الصيدلانية
Joint Authors
al-Ghazzali, Ala Karim Muhammad
Dikran, Sarmad Bahjat
al-Jabburi, Muin Iskandar
Nasir, Ahmad Saib
Source
Ibn al-Haitham Journal for Pure and Applied Science
Issue
Vol. 27, Issue 3 (31 Dec. 2014), pp.339-349, 11 p.
Publisher
University of Baghdad College of Education for Pure Science / Ibn al-Haitham
Publication Date
2014-12-31
Country of Publication
Iraq
No. of Pages
11
Main Subjects
Abstract AR
اقترحت طريقة طيفية بسيطة، دقيقة و مضبوطة لتقدير حامض الميفيناميك في صورتها النقية و في المستحضرات الصيدلانية.
الطريقة المقترحة تستند إلى تفاعل العقار مع الكاشف 2, 1-نفثاكوينون 4-سلفونيك الصوديوم (NQS).
درست الظروف الفضليات من تأثير حجم الكاشف و الدالة الحامضية، زمن التفاعل الأفضل لتكوين المعقد الناتج و كانت مطاوعة قانون بير في مدى تراكيز يتراوح بين 0.5-10.0 مكغم.
مل-1 عند الطول الموجي 450 نانومتر، و حد الكشف 0.189 مكغم.
مل-1.
الطريقة المقترحة طبقت بنجاح لتقدير حامض الميفيناميك في مستحضراته الصيدلانية.
Abstract EN
A simple, accurate and precise spectrophotometric method has been proposed for the determination of Mefenamic acid (MA) in dosage forms.
Proposed method based on the reaction of cited drug with 1,2-Naphthoquinone-4-Sulfonic sodium (NQS).
The optimum experimental condition have been studied.
Beer's Law is obeyed in the concentration range 0.5-10.0 μg / mL at 450 nm with detection limit of 0.189 μg / mL.
Effect of pH, reaction time, and volume of NQS on the determination of Mefenamic acid, have been examined.
The proposed method has been successfully applied for the determination of Mefenamic acid in pharmaceutical preparations.
American Psychological Association (APA)
Dikran, Sarmad Bahjat& al-Jabburi, Muin Iskandar& al-Ghazzali, Ala Karim Muhammad& Nasir, Ahmad Saib. 2014. Spectrophotometric determination of mefenamic acid in pharmaceutical preparations. Ibn al-Haitham Journal for Pure and Applied Science،Vol. 27, no. 3, pp.339-349.
https://search.emarefa.net/detail/BIM-546269
Modern Language Association (MLA)
Dikran, Sarmad Bahjat…[et al.]. Spectrophotometric determination of mefenamic acid in pharmaceutical preparations. Ibn al-Haitham Journal for Pure and Applied Science Vol. 27, no. 3 (2014), pp.339-349.
https://search.emarefa.net/detail/BIM-546269
American Medical Association (AMA)
Dikran, Sarmad Bahjat& al-Jabburi, Muin Iskandar& al-Ghazzali, Ala Karim Muhammad& Nasir, Ahmad Saib. Spectrophotometric determination of mefenamic acid in pharmaceutical preparations. Ibn al-Haitham Journal for Pure and Applied Science. 2014. Vol. 27, no. 3, pp.339-349.
https://search.emarefa.net/detail/BIM-546269
Data Type
Journal Articles
Language
English
Notes
Includes appendices : p. 344-348
Record ID
BIM-546269
