Dyslipidemia in type 1 diabetes mellitus : relation to diabetes duration, glycemic control, body habitus,dietary intake and other epidemiological risk factors
Joint Authors
Hassan, Muna Muhammad
Sahar, Sharaf A.
Hind, Sulayman M.
Nanees, al-Wakil A.
Source
Egyptian Pediatric Association Gazette
Issue
Vol. 63, Issue 2 (30 Jun. 2015), pp.63-68, 6 p.
Publisher
Egyptian Pediatric Association
Publication Date
2015-06-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Topics
Abstract EN
Background: Diabetes is associated with a high risk of cardiovascular disease (CVD).
The classic ‘‘diabetic dyslipidemia’’ is mostly described as hypertriglyceridemia and low levels of HDL-C.
Elevated LDL-C is an established risk factor for CVD.
Objective: Identify the pattern of dyslipidemia in children and adolescents with type 1 diabetes mellitus regularly following at Diabetes Endocrine and Metabolism Pediatric Unit (DEMPU) at Children’s Hospital of Cairo University; and to detect its relation to different risk factors.
Methods: Sixty children and adolescents with T1DM, (34 males and 26 females, mean age 12.5 ± 2.4 years and mean duration of diabetes 4.3± 2.7 years) were evaluated by full history and clinical examination including 3 day dietetic history for analysis, BMI and waist circumference.
Records were revised for mean blood glucose and HbA1c.
Fasting lipid profile (total cholesterol, triglycerides, HDL-C and LDL-C) was performed.
Thirty-nine healthy age and sex matched children were included as control for lipid profile.
Results: Dyslipidemia significantly more frequent among T1DM children and adolescents compared to control subjects (39/60, 65% vs.
11/39, 28.2%, p<0.001); and the dyslipidemic (39/60) compared to normoalbuminuric (21/60) children had significantly higher mean waist circumference.
Both groups were comparable regarding age, age at onset and duration of diabetes, family history of diabetes and CVD, degree of glycemic control and dietary analysis.
Conclusion: Dyslipidemia is significantly more frequent in children and adolescents with T1DM compared to non-diabetic peers.
The most frequent type of dyslipidemia was high LDL-C and low HDL-C in the dyslipidemic group.
American Psychological Association (APA)
Hassan, Muna Muhammad& Sahar, Sharaf A.& Hind, Sulayman M.& Nanees, al-Wakil A.. 2015. Dyslipidemia in type 1 diabetes mellitus : relation to diabetes duration, glycemic control, body habitus,dietary intake and other epidemiological risk factors. Egyptian Pediatric Association Gazette،Vol. 63, no. 2, pp.63-68.
https://search.emarefa.net/detail/BIM-591905
Modern Language Association (MLA)
Nanees, al-Wakil A.…[et al.]. Dyslipidemia in type 1 diabetes mellitus : relation to diabetes duration, glycemic control, body habitus,dietary intake and other epidemiological risk factors. Egyptian Pediatric Association Gazette Vol. 63, no. 2 (Jun. 2015), pp.63-68.
https://search.emarefa.net/detail/BIM-591905
American Medical Association (AMA)
Hassan, Muna Muhammad& Sahar, Sharaf A.& Hind, Sulayman M.& Nanees, al-Wakil A.. Dyslipidemia in type 1 diabetes mellitus : relation to diabetes duration, glycemic control, body habitus,dietary intake and other epidemiological risk factors. Egyptian Pediatric Association Gazette. 2015. Vol. 63, no. 2, pp.63-68.
https://search.emarefa.net/detail/BIM-591905
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 67-68
Record ID
BIM-591905