Synthesis, characterization and study the biological activity of new morpholine derivative
Other Title(s)
تحضير و تشخيص مشتقات جديدة للمورفولين و دراسة الفعالية البايولوجية لها
Joint Authors
al-Qaysi, Sura Sadiq
al-Tamimi, Intisar Uayd Prisse
al-Bayati, Samiah Jumah Khammas
Source
Issue
Vol. 12, Issue 4 (31 Dec. 2015), pp.761-773, 13 p.
Publisher
University of Baghdad College of Science for Women
Publication Date
2015-12-31
Country of Publication
Iraq
No. of Pages
13
Main Subjects
Topics
Abstract EN
A new series of morpholine derivative were prepared by reacting the morpholine with ethyl chloro acetate in the presence triethylamine as an catalyst and benzene as a solvent gave the ethyl morpholin-4-ylacetate reaction with hydrazine hydrate and ethanol as a solvent gave the 2-(morpholin-4-yl)acetohydrazide gave series of Schiff base were prepared by reacting 2-(morpholin-4- yl)acetohydrazide with different aromatic aldehydes and ketons .
The new series of (3-9 )were synthesis by reaction of Schiff base (10-14) with chloroacetyl chloride, triethyl amine as an catalyst and 1,4dioxane as a solvent .The chemical structures of the synthesis compound were identified by spectral methods their [ IR ,1H-NMR and 71C-NMR ].The synthesised compounds were screened for antibacterial activity and antifungal activity promising by disc diffusion method by measuring the zone of inhibition and the results were compared to standard drugs ciprofloxacin .
American Psychological Association (APA)
al-Tamimi, Intisar Uayd Prisse& al-Bayati, Samiah Jumah Khammas& al-Qaysi, Sura Sadiq. 2015. Synthesis, characterization and study the biological activity of new morpholine derivative. Baghdad Science Journal،Vol. 12, no. 4, pp.761-773.
https://search.emarefa.net/detail/BIM-654412
Modern Language Association (MLA)
al-Tamimi, Intisar Uayd Prisse…[et al.]. Synthesis, characterization and study the biological activity of new morpholine derivative. Baghdad Science Journal Vol. 12, no. 4 (2015), pp.761-773.
https://search.emarefa.net/detail/BIM-654412
American Medical Association (AMA)
al-Tamimi, Intisar Uayd Prisse& al-Bayati, Samiah Jumah Khammas& al-Qaysi, Sura Sadiq. Synthesis, characterization and study the biological activity of new morpholine derivative. Baghdad Science Journal. 2015. Vol. 12, no. 4, pp.761-773.
https://search.emarefa.net/detail/BIM-654412
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 771-772
Record ID
BIM-654412