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Synthesis,characterization of some metal complexes with bis[ O, O-2, 3; O, O-5, 6-(thiol (carboxylic) methylidene)]-L-ascorbic acidand studies their biological activity
Joint Authors
Waddai, Fawzi Yahya
al-Waswi, Falih Hasan Musa Muhammad
Fadil, Huda Ahmad
Source
Journal of Kufa for Chemical Science
Issue
Vol. 1, Issue 10 (30 Nov. 2015), pp.38-55, 18 p.
Publisher
University of Kufa Faculty of Education for Women Department of Chemistry
Publication Date
2015-11-30
Country of Publication
Iraq
No. of Pages
18
Main Subjects
Abstract EN
The reaction of bis[O,O-2,3;O,O-5,6-(chloro(carboxylic)methylidene)]-L-ascorbic acid with the excess of Sodium sulfide gave new product bis[O,O-2,3;O,O-5,6-(Thiol(carboxylic)methylidene)]-L ascorbic acid(LS), which was isolated and characterized by 1H,13C-NMR, elemental analysis (C.H.N S), mass spectroscopy, UV-visible and Fourier Transform infrared (FTIR) methods.
The complexes of the ligand (LS) with metal ions, M2+= (Cu, Co, Ni, Cd, Hg) and Cr3+ were synthesized and characterized by FTIR, UV-Visible, molar conductance, atomic absorption, magnetic susceptibility, elemental analysis (C.H.N.S) methods.
The analysis showed that the ligand (LS) is coordinating with metal ions through the tetradentate carboxylato and thiol groups manner resulting in six-coordinated metal ion in an octahedral geometry.
The TLC for (LS) and complexes showed one spot for each indicating the purity of these compounds.
The study of biological activity of the ligand (LS) and (Co2+, Cu2+, Cd2+) complexes showed various activities toward two types of pathogenic bacteria are Staphylococcus aureus and Escherichia coli.
American Psychological Association (APA)
Waddai, Fawzi Yahya& al-Waswi, Falih Hasan Musa Muhammad& Fadil, Huda Ahmad. 2015. Synthesis,characterization of some metal complexes with bis[ O, O-2, 3; O, O-5, 6-(thiol (carboxylic) methylidene)]-L-ascorbic acidand studies their biological activity. Journal of Kufa for Chemical Science،Vol. 1, no. 10, pp.38-55.
https://search.emarefa.net/detail/BIM-687389
Modern Language Association (MLA)
Waddai, Fawzi Yahya…[et al.]. Synthesis,characterization of some metal complexes with bis[ O, O-2, 3; O, O-5, 6-(thiol (carboxylic) methylidene)]-L-ascorbic acidand studies their biological activity. Journal of Kufa for Chemical Science Vol. 1, no. 10 (Nov. 2015), pp.38-55.
https://search.emarefa.net/detail/BIM-687389
American Medical Association (AMA)
Waddai, Fawzi Yahya& al-Waswi, Falih Hasan Musa Muhammad& Fadil, Huda Ahmad. Synthesis,characterization of some metal complexes with bis[ O, O-2, 3; O, O-5, 6-(thiol (carboxylic) methylidene)]-L-ascorbic acidand studies their biological activity. Journal of Kufa for Chemical Science. 2015. Vol. 1, no. 10, pp.38-55.
https://search.emarefa.net/detail/BIM-687389
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 55
Record ID
BIM-687389