Determination of mefenamic acid using a new mode of irradiation (array of six identical LEDs) and detection (twin solar cells) through turbidity measurement by CFIA
Other Title(s)
تقدير حامض الميفيناميك باستخدام نمط جديد من التشعيع (مصفوفة متشابهة لستة ثنائيات وصلة باعثة) و التحسس (اثنان من الخلايا الشمسية) خلال قياس التعكرية بوساطة التحليل بالحقن الجرياني المستمر
Joint Authors
al-Saidi, Mustafa Karim Kazim
al-Awwadi, Nagham Shakir Turki
Source
Issue
Vol. 57, Issue 2B (30 Jun. 2016), pp.1052-1070, 19 p.
Publisher
University of Baghdad College of Science
Publication Date
2016-06-30
Country of Publication
Iraq
No. of Pages
19
Main Subjects
Topics
Abstract EN
A newly developed analytical method characterized by its speed and sensitivity for the determination of mefenamic acid (MFA) in pure and pharmaceutical preparation is established via turbidimetric measurement (0-180o) by Ayah 6SX1-ST-2D Solar cell CFI Analyser .
The method was based on the reaction of phosphomolybdic acid with mefenamic acid in aqueous medium to form blue color precipitate as an ion-pair complex .
Turbidity was measured via the reflection of incident light that collides on the surface precipitated particles at 0-180o .
The chemical and physical parameters were studied and optimized.
The calibration graph was linear in the range of 0.3-7 or 0.3-10 mMol.L-1, with correlation coefficient r = 0.9907 or 0.9556 respectively.
The limit of detection 4.92 μg/sample from the step wise dilution for the minimum concentration in the linear dynamic ranged of the calibration graph with RSD% lower than 0.3% for 3 and 5 mMol.L-1 ( n= 6,10 respectively ) concentration of mefenamic acid.
The method was successfully applied to the determination of mefenamic acid in four pharmaceuticals .
A comparison was made between the newly developed method analysis and the classical method , in addition to between four different pharmaceutical preparations (UV- spectrophotometry at wave length 222 nm) using the standard additions method via the use of t-test.
It was noticed that there was no significant difference between two methods at 95 % confidence level and significant difference between four drugs.
American Psychological Association (APA)
al-Awwadi, Nagham Shakir Turki& al-Saidi, Mustafa Karim Kazim. 2016. Determination of mefenamic acid using a new mode of irradiation (array of six identical LEDs) and detection (twin solar cells) through turbidity measurement by CFIA. Iraqi Journal of Science،Vol. 57, no. 2B, pp.1052-1070.
https://search.emarefa.net/detail/BIM-688384
Modern Language Association (MLA)
al-Awwadi, Nagham Shakir Turki& al-Saidi, Mustafa Karim Kazim. Determination of mefenamic acid using a new mode of irradiation (array of six identical LEDs) and detection (twin solar cells) through turbidity measurement by CFIA. Iraqi Journal of Science Vol. 57, no. 2B (2016), pp.1052-1070.
https://search.emarefa.net/detail/BIM-688384
American Medical Association (AMA)
al-Awwadi, Nagham Shakir Turki& al-Saidi, Mustafa Karim Kazim. Determination of mefenamic acid using a new mode of irradiation (array of six identical LEDs) and detection (twin solar cells) through turbidity measurement by CFIA. Iraqi Journal of Science. 2016. Vol. 57, no. 2B, pp.1052-1070.
https://search.emarefa.net/detail/BIM-688384
Data Type
Journal Articles
Language
English
Notes
Text in English ; abstracts in English and Arabic.
Record ID
BIM-688384